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Max-Planck-Institut für molekulare Zellbiologie und Genetik (MPI-CBG)

Address Pfotenhauerstraße 108
01307 Dresden
Deutschland

GERiT This institution in GERiT

01307 Dresden

Projects

Priority Programmes
- Current projects
  - The role of membrane protein phase separation in nuclear membrane sealing and fusion
    (Applicant von Appen, Alexander )
- Completed projects
Research Grants
- Current projects
  - Identifying the epigenetic regulatory mechanisms that drive the response of liver ductal cells to damage
    (Applicants Dahl, Andreas ; Huch, Meritxell )
  - Understanding how animals generate and regenerate cell diversity integrating live imaging, lineage tracking, deep learning and big image visualization
    (Applicants Haase, Robert ; Tomancak, Pavel )
- Completed projects
Clinical Research Units
- Completed projects
  - Quantitative Charakterisierung von Protein-Sekretionsmustern in Caspase-1-assoziierten Sekretomen
    (Applicant Shevchenko, Andrej )
Research Units
- Current projects
- Completed projects
  - FOR 2038: Nanopatterned Organic Matrices in Biological Silica Mineralisation
    (Spokesperson Kröger, Nils )
  - FOR 2682: Seasonal temperature acclimation in Drosophila
    (Spokesperson Brankatschk, Ph.D., Marko )
  - Lipidome Dynamics during Drosophila Acclimation to Diet and Temperature
    (Applicant Shevchenko, Andrej )
  - Proteins and Membrane Compartments involved in Silica Biogenesis
    (Applicants Kröger, Nils ; Shevchenko, Andrej )
WBP Position
- Current projects
Collaborative Research Centres
- Completed projects
  - Apikaler und basolateraler Membrantransport in MDCK Zellen
    (Project Head Simons, Kai )
  - Basolateral ciliogenesis, basal progenitor delamination, and the formation of the subventricular zone in developing neocortex
    (Project Head Huttner, Wieland B. )
  - Differentiation and maintenance of zebrafish photoreceptor polarity
    (Project Head Knust, Elisabeth )
  - Kontrolle der Epitheldifferenzierung von Drosophila melanogaster
    (Project Head Knust, Elisabeth )
  - Molekulare Mechanismen der Bildung sekretorischer Vesikel vom Trans-Golgi-Netzwerk
    (Project Head Huttner, Wieland B. )
  - SFB 655: Cells into Tissues: Stem Cell and Progenitor Commitment and Interactions during Tissue Formation
    (Spokesperson Ehninger, Gerhard )
  - Structure, function, and dynamics of SLC26 and NCS2 transporters
    (Project Head Geertsma, Eric )
  - The role of runx1 in haematopoietic stem cells
    (Project Head Buchholz, Frank )
  - Towards a morphological and evolutionary understanding of non-apical progenitors in the zebrafish retina
    (Project Head Norden, Caren )
  - Vascular tube formation
    (Project Head Lammert, Eckhard )
CRC/Transregios
- Completed projects
  - Investigation of molecular mechanisms responsible for the phenotype of caveolin-1 KO-mice
    (Project Head Kurzchalia, Teymuras )
  - Lipid fluorescence microscopy
    (Project Head Thiele, Christoph )
  - Lipid-protein interactions in rafts
    (Project Head Simons, Kai )
  - Lipid raft clustering in Membrane trafficking
    (Project Head Simons, Kai )
  - Lipid rafts and obesity: function of OBR-GRP and endospanin, two lipid raft-associated tetraspanins, in the leptin recceptor trafficking
    (Project Head Hoflack, Bernard )
  - Measuring dynamics of native lipid species in living cells
    (Project Head Nadler, André Georg )
  - Patched-dependent regulation of intracellular endocannabinoid trafficking and its function in signalling and metabolism
    (Project Heads Eaton, Suzanne ; Nadler, André Georg ; Zerial, Ph.D., Marino )
  - Physiological funkction of the cholesterol-interacting, lipid raft-associated plasma membrane protein prominin: from cell biology to human disease
    (Project Heads Corbeil, Denis ; Huttner, Wieland B. )
  - Prominin/membrane-lipid assemblies and their relevance for apical plasma membrane protrusions
    (Project Heads Corbeil, Denis ; Huttner, Wieland B. )
  - Quantitative Profiling of Phospholipids and Glycolipids by Quadrupole Time-of-Flight Mass Spectrometry
    (Project Head Shevchenko, Andrej )
  - Shotgun lipidomics by high resolution tandem mass spectrometry
    (Project Head Shevchenko, Andrej )
  - Synthetic actomyosin-membrane cortex
    (Project Head Grill, Stephan Wolfgang )
  - Synthetic endosomes
    (Project Head Zerial, Ph.D., Marino )
  - TRR 13: Membrane Microdomains and Their Role in Human Disease
    (Spokesperson Schmitz, Gerd )
  - TRR 83: Molecular Architecture and Cellular Functions of Lipid/Protein Assemblies
    (Spokesperson Söllner, Thomas )
Research data and software
- Completed projects
  - Fiji Software Sustainability
    (Applicants Jug, Florian ; Tomancak, Pavel )
Research Fellowships
- Completed projects
  - Molecular basis of ESCRT-mediated sealing of the nuclear envelope.
    (Applicant von Appen, Alexander )
Major Instrumentation Initiatives
- Completed projects
  - New generation laser scanning confocal microscope for multimodal deep tissue and functional imaging
International Research Training Groups
- Current projects
  - GRK 2251: Immunological and Cellular Strategies in Metabolic Disease (ICSMD)
    (Spokesperson Bornstein, Ph.D., Stefan R. )
Graduate Schools
- Completed projects
  - GSC 97: Dresden International Graduate School for Biomedicine and Bioengineering (DIGS-BB)
    (Spokesperson Rödel, Gerhard )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 2068: Physics of Life - The Dynamic Organization of Living Matter (PoL)
    (Spokespersons Campas, Otger ; Eaton, Suzanne ; Grill, Stephan Wolfgang ; Schiessel, Helmut )
Clusters of Excellence
- Completed projects
  - EXC 168: Regenerative Therapies - From Cells to Tissues to Therapies: Engineering the Cellular Basis of Regeneration
    (Spokespersons Bonifacio, Ph.D., Ezio ; Brand, Michael ; Calegari, Ph.D., Federico ; Tanaka, Ph.D., Elly Margaret )
  - EXC 1056: Center for Advancing Electronics Dresden (cfAED)
    (Spokesperson Fettweis, Gerhard P. )

Subinstitutions

Zentrum für Systembiologie Dresden (CSBD)

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