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Institution

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Universität Leipzig
Institut für Biochemie
Arbeitsgruppe Biochemie und Bioorganische Chemie

Address Brüderstraße 34
04103 Leipzig
Deutschland

GERiT This institution in GERiT

04103 Leipzig

Projects

Research Grants
- Current projects
  - Structure Elucidation of the Neuropeptide Y5 Receptor- Relevant in Food intake and Cancer
    (Applicant Beck-Sickinger, Annette G. )
- Completed projects
Clinical Research Units
- Completed projects
  - Atherobesity: Molekulare Mechanismen
    (Applicant Beck-Sickinger, Annette G. )
Collaborative Research Centres
- Current projects
  - Central Administration
    (Project Head Beck-Sickinger, Annette G. )
  - Characterizing the molecular interactions between Y receptors and arrestin
    (Project Heads Beck-Sickinger, Annette G. ; Huster, Daniel )
  - Development of modulators at the chemokine-like receptor to elucidate its role in obesity
    (Project Heads Beck-Sickinger, Annette G. ; Meiler, Jens )
  - Molecular mechanisms of allosteric modulators at Y-receptors
    (Project Head Beck-Sickinger, Annette G. )
  - Peptide synthesis and membrane protein (GPCR) expression
    (Project Heads Beck-Sickinger, Annette G. ; Scheerer, Patrick )
  - SFB 1423: Structural Dynamics of GPCR Activation and Signaling
    (Spokesperson Beck-Sickinger, Annette G. )
  - Targeted delivery of drugs into adipocytes by peptide-mediated shuttling in a new obesity mouse model
    (Project Heads Beck-Sickinger, Annette G. ; Klöting-Blüher, Nora )
  - Targeting of central peptide receptors via nasal ligand application to modulate food intake
    (Project Heads Bechmann, Ingo ; Beck-Sickinger, Annette G. ; Klöting-Blüher, Nora ; Schulz, Angela )
- Completed projects
  - Molecular Mechanisms of Action of Adipokines
    (Project Head Beck-Sickinger, Annette G. )
  - On the role of protein loops in the biosynthesis and in the ligand-receptor interaction of the neuropeptide Y system
    (Project Head Beck-Sickinger, Annette G. )
  - SFB 610: Variation in Protein Conformation: Cellbiological and Pathological Relevance
    (Spokesperson Beck-Sickinger, Annette G. )
  - Zentrale Aufgaben des Sonderforschungsbereichs
    (Project Head Beck-Sickinger, Annette G. )
Research Units
- Completed projects
  - Markierung von Peptidhormonen mit Metallkomplexen für Tumordiagnostik und -therapie
    (Applicants Beck-Sickinger, Annette G. ; Neundorf, Ines )
CRC/Transregios
- Completed projects
  - Chemical modification of proteins for the characterization of matrix-protein interactions
    (Project Head Beck-Sickinger, Annette G. )
  - Integrated Research Training Group "Matrix Engineering"
    (Project Heads Beck-Sickinger, Annette G. ; Scharnweber, Dieter ; Werner, Carsten )
Priority Programmes
- Completed projects
  - Peptide-templated bioconjugation of proteins on and in live cells for studies of GPCR trafficking and crosstalk
    (Applicants Beck-Sickinger, Annette G. ; Seitz, Oliver )
Research Fellowships
- Completed projects
  - Directed evolution of bacterial polysialyltransferases for structural studies and their application for enzymatic polysialylation of therapeutic proteins
    (Applicant Baumann, Lars )
Major Research Instrumentation
- Completed projects
  - Konfokales High-Content Imaging System
  - MALDI-ToF mass spectrometer
Research Training Groups
- Completed projects
  - GRK 378: Mechanisms and Applications of Non-Conventional Oxidation Reactions
    (Spokesperson Hey-Hawkins, Evamarie )
Graduate Schools
- Completed projects
  - GSC 185: Leipzig School of Natural Sciences - Building with Molecules and Nano-objects (BuildMoNa)
    (Spokesperson Hey-Hawkins, Evamarie )

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