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Project Details

Institution

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Christian-Albrechts-Universität zu Kiel
Institut für Experimentelle Medizin (IEM)
Arbeitsgruppe Systemische Proteomics und Bioanalytik

Address Niemannsweg 11
24105 Kiel
Deutschland

GERiT This institution in GERiT

24105 Kiel

Projects

Major Research Instrumentation
- Completed projects
  - Elektrospray Massenspektrometer mit ETD, HCD und UVPD, inklusive nanoUHPLC
  - LC-MS/MS Massenspektrometer
Research Grants
- Current projects
  - Differential cellular proteomics of human apolipoprotein E (APOE) and determination of its interaction with mitochondria-associated membranes and proteins
    (Applicants Hübbe, Patricia ; Tholey, Andreas )
- Completed projects
  - The task of the S100 Fused-Type Protein Hornerin in skin defense
    (Applicants Tholey, Andreas ; Weidinger, Stephan )
  - Yersinia-induced deregulation of cellular life and death signals in macrophages
    (Applicants Ruckdeschel, Klaus ; Tholey, Andreas )
Priority Programmes
- Current projects
  - Proteomics and peptidomics for the identification and functional characterization of sORF encoded proteins
    (Applicants Becher, Dörte ; Tholey, Andreas )
Research Units
- Current projects
  - Cultivation and characterization of IBD-relevant microbes
    (Applicants Rupp, Jan ; Tholey, Andreas )
  - FOR 5042: The microbiome as a therapeutic target in inflammatory bowel diseases
    (Spokesperson Franke, Andre )
Collaborative Research Centres
- Current projects
  - Evolutionary dynamics and molecular basis of C.elegans-microbiome interactions
    (Project Heads Dierking, Katja ; Kaleta, Christoph ; Leippe, Matthias ; Schulenburg, Hinrich ; Tholey, Andreas )
  - Next generation sequencing, proteomics, and metabolomics applications for studying Metaorganisms
    (Project Heads Baines, John F. ; Häsler, Robert ; Liebeke, Manuel ; Rosenstiel, Ph.D., Philip Caspar ; Tholey, Andreas )
- Completed projects
  - Mass Spectrometry based proteomics for the analysis of proteolytic events
    (Project Heads Janßen, Ottmar ; Leippe, Matthias ; Tholey, Andreas )
Major Instrumentation Initiatives
- Completed projects
  - Evaluation and validation of MALDI-IMS in molecular pathology
    (Applicant Röcken, Christoph )

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