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Institution
Rheinische Friedrich-Wilhelms-Universität Bonn
Medizinische Fakultät
Medizinische Klinik und Poliklinik I - Allgemeine Innere Medizin
Address
Venusberg-Campus 1
53127 Bonn
Deutschland
GERiT
This institution in GERiT
53127 Bonn
Projects
Research Grants
Current projects
Modulation of dead cell disposal and inflammatory signaling as novel approach to peritoneal membrane preservation in dialysis
(Applicant
von Vietinghoff, Sibylle
)
Completed projects
Adenoviral- or bile acid-mediated transfer of therapeutic neucleid acids in hepatocytes to inhibit Hepatitis C in viral translation in vitro and in vivo
(Applicant
Caselmann, Wolfgang
)
Analysis and modification of the metabolic antioxidative balance as risk factor for liver fibrosis in humanized, transgenic UGT1A SNP and wild type mice
(Applicant
Strassburg, Christian
)
Immunmodulation durch induzierte Antigen-spezifische regulatorische T-Zellen bei der chronischen Hepatitis C Infektion
(Applicant
Spengler, Ulrich
)
Klinische Studien - Vorbereitungskosten
(Applicant
Sauerbruch, Tilman
)
Mediators of vascular inflammation and tertiary lymphoid organ formation in chronic kidney disease
(Applicant
von Vietinghoff, Sibylle
)
Pathophysiologische Bedeutung der Gallensäure beta-Glukosidase (GBA2): Untersuchungen an GBA2-defizienten Mäusen, Mutationsanalysen von M. Gaucher Patienten am GBA2-Gen
(Applicants
van Echten-Deckert, Ph.D., Gerhild
;
Yildiz, Yildiz
)
Role of hepatic CD49a+ Natural Killer cells for hepatitis C virus infection
(Applicant
Krämer, Benjamin
)
The role of renal impairment in atherosclerotic inflammation
(Applicant
von Vietinghoff, Sibylle
)
Ttoxicity analyses and therapeutic modification of the anti-cancer drug camptothecin
(Applicant
Strassburg, Christian
)
Tumour associated microparticles as a novel biomarker in HCC and CCA
(Applicant
Kornek, Miroslaw
)
Urolithiasis: Entwicklung und Validierung eines massenspektrometrischen Verfahrens zur Messung der gastrointestinalen Oxalsäureabsorption
(Applicant
von Unruh, Gerd
)
Zytoprotektive und metabolische Rolle der UDP-Glukuronosyltransferasen (UGT) in der Karzinogenese gastrointestinaler Tumoren
(Applicant
Strassburg, Christian
)
Priority Programmes
Completed projects
Kombinierte CpG-Oligodeoxynukleotid/Lipopeptid Liposomen als neuer immunmodulatorischer Impfstoff gegen Hepatitis C Virus Infektion
(Applicant
Spengler, Ulrich
)
Regulation of functional heterogeneity and plasticity of human tissue-bound ILC3
(Applicant
Nattermann, Jacob
)
Heisenberg Fellowships
Completed projects
Experimentelle Gastroenterologie
(Applicant
Strassburg, Christian
)
Clinical Research Units
Completed projects
Charakterisierung der Rolle von Metabolisierungsenzym- und Transporter-Polymorphismen beim hepatozellulären Karzinom (HCC)
(Applicant
Strassburg, Christian
)
Research Units
Current projects
FOR 5427: BActerial Renal InfeCtion And DEfense (BARICADE)
(Spokesperson
Wagenlehner, Florian
)
Protection from pyelonephritis during glucosuria
(Applicant
von Vietinghoff, Sibylle
)
Collaborative Research Centres
Current projects
Myeloid immune cell subsets and the renal microenvironment in glomerulonephritis
(Project Heads
Kurts, Christian
;
von Vietinghoff, Sibylle
)
Completed projects
Regulation of immune functions by alternative antigen presentation in HIV and HCV infection
(Project Heads
Nattermann, Jacob
;
Spengler, Ulrich
)
The molecular basis and genetic variability of mucosal UDP-glukuronosyltransferase (UGT) gene regulation in humans and the humanized UGTIA-SNP-C57BL/6 mouse model
(Project Head
Strassburg, Christian
)
Research Fellowships
Completed projects
Induction of fibrolytic activity in hepatic stellate cells by T cell derived microparticles in vitro and in vivo
(Applicant
Kornek, Miroslaw
)
Regulation of neutrophil homeostasis by IL-17A and IL-17F-producing gamma-delta-T-cells
(Applicant
von Vietinghoff, Sibylle
)
CRC/Transregios
Completed projects
Angiotensin stimulated hepatic fibrogenesis and portal hypertension: Receptor regulation and intracellular signaling
(Project Heads
Sauerbruch, Tilman
;
Trebicka, Ph.D., Jonel
)
Regulation of Hepatic Carcinogen-metabolizing UGT1A Genes and HCC Development in the Humanized UHT1A-SNP Mouse
(Project Heads
Manns, Michael Peter
;
Strassburg, Christian
)
Role of innate lymphoid cells in liver fibrosis
(Project Heads
Nattermann, Jacob
;
Spengler, Ulrich
)
Clinical Trials
Completed projects
Covered transjugular intrahepatic portosystemic stent shunt versus optimezed medical treatment for the secondary prevention of variceal bleeding in cirrhosis
(Applicant
Sauerbruch, Tilman
)
Additional Information
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