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Project Details

Institution

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Heinrich-Heine-Universität Düsseldorf
Institut für Pharmazeutische und Medizinische Chemie

Address Universitätsstraße 1
40225 Düsseldorf
Deutschland

GERiT This institution in GERiT

40225 Düsseldorf

Projects

Research Units
- Current projects
  - FOR 2518: Functional dynamics of ion channels and transporters - DynIon -
    (Spokesperson Benndorf, Klaus )
- Completed projects
  - Disinhibition and inhibition of HCN2 channel function by ligand binding to the cyclic nucleotide binding domain
    (Applicant Gohlke, Holger )
Priority Programmes
- Current projects
  - Chitin oligosaccharide recognition by human chitinase-like proteins: Deciphering CodeChi at the atomistic level and its impact on cellular signaling
    (Applicants Cramer, Jonathan ; Gohlke, Holger )
- Completed projects
  - Targeting spectrin redox switches to regulate the mechanoproperties of red blood cells.
    (Applicants Cortese-Krott, Miriam Margherita ; Gohlke, Holger )
Research Grants
- Current projects
- Completed projects
Major Research Instrumentation
- Completed projects
  - High Content Analysis-Imager (HCAI)
  - Multifunktionale biologische Screening-Einheit
Collaborative Research Centres
- Current projects
  - Acquisition – Processing – Sharing – Storage: Research data management for interdisciplinary membrane research
    (Project Heads Gohlke, Holger ; Weidtkamp-Peters, Stefanie )
  - Functional state modulation of membrane proteins by dynamic association and dissociation
    (Project Head Gohlke, Holger )
- Completed projects
  - Integriertes Graduiertenkolleg
    (Project Heads Gohlke, Holger ; Keitel-Anselmino, Verena )
  - Structural models and conformational dynamics of the G protein coupled bile acid receptor TGR5
    (Project Heads Gohlke, Holger ; Keitel-Anselmino, Verena ; Seidel, Claus )
Core Facilities
- Completed projects
  - Improvement of the central microscopy research infrastructure Center for Advanced Imaging (CAi) at Heinrich Heine University Düsseldorf
    (Applicant Weidtkamp-Peters, Stefanie )
Research Training Groups
- Current projects
  - GRK 2158: Natural products and natural product analogs against therapy-resistant tumors and microorganisms: new lead structures and modes of action
    (Spokesperson Gohlke, Holger )

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