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Institution
Universitätsklinikum Essen
Klinik für Dermatologie
Address
Hufelandstraße 55
45147 Essen
Deutschland
GERiT
This institution in GERiT
45147 Essen
Projects
Research Grants
Current projects
Chronic/latent viral infections modulate the function of cytotoxic T cells and natural killer cells with antitumor activity
(Applicants
Dittmer, Ulf
;
Paschen, Annette
)
Dissecting DNA methylation changes arising during transition of melanocytes to various melanocytic lesions of the skin and uvea.
(Applicants
Griewank, Klaus Georg
;
Zeschnigk, Michael
)
Genetic analysis of cutaneous adnexal tumors
(Applicants
Griewank, Klaus Georg
;
Utikal, Jochen
)
Molecular Analysis of the TSC Complex
(Applicants
Kümmel, Daniel
;
Oeckinghaus, Andrea
)
Promoting Excellence in Medicine: The University Medicine Essen Clinician Scientist Academy (UMEA)
(Applicant
Führer-Sakel, Dagmar
)
Ral GTPases as novel regulators of acinar cell plasticity in the pancreas – implications for cancer development and treatment
(Applicant
Oeckinghaus, Andrea
)
Completed projects
Analysis and therapeutic targeting of the metabolic and proliferative tumor heterogeneity in malignant melanoma
(Applicant
Roesch, Alexander
)
Chemoresistenzmechanismen beim humanen malignen Melanom
(Applicant
Schadendorf, Dirk
)
Entwicklung neuer Behandlungsstrategien zur Therapie des Melanom
(Applicant
Schadendorf, Dirk
)
Functional analysis of genetic alterations occuring in uveal melanoma
(Applicant
Griewank, Klaus Georg
)
Genetic variants associated with melanoma susceptibility and overall survival
(Applicant
Schadendorf, Dirk
)
Identification and characterization of receptor- and transport proteins for uptake and intracellular migration of plasmid DNA in keratinocytes
(Applicant
Hengge, Ulrich R.
)
Identifikation tumorspezifischer Antigene des kutanen T-Zell-Lymphoms mit Hilfe der SEREX-Methode
(Applicant
Eichmüller, Stefan
)
Novel tumor suppressors in pancreatic adenocarcinoma
(Applicant
Oeckinghaus, Andrea
)
Role of Regulatory T cells for the pathogenesis of Autoimmune Blistering Diseases
(Applicants
Enk, Alexander
;
Hadaschik, Eva
)
Wissens- und datenbasierte Personalisierung von Medizin am Point of Care
(Applicant
Böckmann, Britta
)
Clinical Research Units
Current projects
Building health intelligence with complex data on tumor cell states and therapy resistance
(Applicants
Horn, Susanne
;
Schadendorf, Dirk
)
Coordination Funds
(Applicant
Roesch, Alexander
)
Dissecting and targeting HLA class II-positive melanoma cell states in therapy resistance
(Applicant
Paschen, Annette
)
Epigenetic maintenance of the redox balance in therapy-persisting tumor cell states
(Applicant
Roesch, Alexander
)
KFO 337: Phenotypic Therapy and Immune Escape in Cancer (PhenoTImE): pre-clinical and translational advance of the CRU 337
(Spokesperson
Schadendorf, Dirk
)
Independent Junior Research Groups
Current projects
Discovering novel metabolic vulnerabilities in melanoma metastasis
(Applicant
Tasdogan, Alpaslan
)
Research Fellowships
Completed projects
Analyse der zur Entartung führenden Signaltransduktionswege in G alpha q (GNAQ) Genmutation tragenden Aderhaut-Melanomen
(Applicant
Griewank, Klaus Georg
)
Functional studies on the kB-Ras proteins
(Applicant
Oeckinghaus, Andrea
)
Regulation of Histone Deacetylases and long noncoding RNAs in malignant melanoma and their functional relevance in mediating resistance mechanisms induced by BRAF inhibitor treatment
(Applicant
Heinemann, Anja
)
Collaborative Research Centres
Current projects
IFNy-induced cell state transition in melanoma
(Project Head
Paschen, Annette
)
Molecular regulation of differentiation and cell cycle in tumor-repopulating melanoma cells
(Project Head
Roesch, Alexander
)
CRC/Transregios
Current projects
Role of T cell subsets in the pathogenesis of autoimmune blistering disease
(Project Heads
Enk, Alexander
;
Hadaschik, Eva
)
Treatment expectation in clinical and experimental inflammatory skin conditions
(Project Heads
Benson, Sven
;
Schedlowski, Manfred
;
Sondermann, Wiebke
)
Clinical Trials
Current projects
Randomized Clinical Trial Comparing Sentinel Lymph Node Excision (SLNE) with or without preoperative hybrid "single-photon emission computed tomography/computed tomography" (SPECT/CT) in Melanoma. (SNEPS-Trial)
(Applicant
Klode, Joachim
)
Research Training Groups
Current projects
GRK 2535: Knowledge- and data-driven personalization of medicine at the point of care
(Spokesperson
Nensa, Felix
)
Additional Information
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