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Institution

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Goethe-Universität Frankfurt am Main
Fachbereich Biowissenschaften
Institut für Zellbiologie und Neurowissenschaft

Address Max-von-Laue-Straße 13
60438 Frankfurt am Main
Deutschland

GERiT This institution in GERiT

60438 Frankfurt am Main

Projects

Research Grants
- Current projects
  - Deciphering the role of soluble epoxide hydrolase in homeostasis with Chemical Biology tools
    (Applicants Fleming, Ph.D., Ingrid ; Hefendehl, Jasmin Kim ; Proschak, Eugen )
  - The blood brain barrier as target for mental resilience and susceptibility
    (Applicants Schweiger, Susann ; Segarra, Marta )
- Completed projects
Research Units
- Current projects
  - FOR 2325: Interactions at the Neurovascular Interface
    (Spokesperson Adams, Ralf H. )
- Completed projects
  - FOR 2251: Adaptation and Persistence of the Emerging Pathogen Acinetobacter baumannii
    (Spokesperson Müller, Volker )
  - Instructive roles of the vasculature during neuronal arborization and spine morphogenesis
    (Applicant Acker-Palmer, Amparo )
  - Nucleotide receptors govern proliferation and differentiation of human neural stem cells
    (Applicant Zimmermann, Herbert )
  - Rolle GABAerger Inhibition bei auditorischer Maskierung im primären Hörkortex
    (Applicant Kössl, Manfred )
  - The role of pericytes in vascular amyloidosis
    (Applicant Hefendehl, Jasmin Kim )
  - The source of genomic innovation in the human pathogen Acinetobacter baumannii
    (Applicant Ebersberger, Ingo )
  - Zentralprojekt
    (Applicant Klump, Georg M. )
Priority Programmes
- Current projects
  - Role of the cell junction-assocaited mechanical forces in the regulation of organ size in zebrafish
    (Applicant Lecaudey, Virginie )
- Completed projects
Research Fellowships
- Completed projects
Heisenberg Professorships
- Completed projects
  - Structural Cell Biology
    (Applicant Eimer, Stefan )
Independent Junior Research Groups
- Completed projects
  - Exploring the phosphoinositide network to modulate plant cell polarity
    (Applicant Heilmann, Ingo )
  - Pericytes – a common link in the comorbidity of vascular impairment and Alzheimer’s Disease
    (Applicant Hefendehl, Jasmin Kim )
WBP Position
- Completed projects
  - Investigating the mechanisms by which cells coordinate their movements within a migrating cell group using the zebrafish lateral line
    (Applicant Lardennois, Alicia )
Heisenberg Grants
- Completed projects
  - Structural Cell Biology
    (Applicant Eimer, Stefan )
Collaborative Research Centres
- Current projects
  - Central tasks of the CRC
    (Project Heads Acker-Palmer, Amparo ; Nitsch, Robert )
  - Dynamics of membrane receptor clustering in endothelial cells
    (Project Head Acker-Palmer, Amparo )
  - Imaging and phenotypical screening platform
    (Project Heads Eimer, Stefan ; Heilemann, Mike ; Pohl, Christian ; Stolz, Alexandra ; Wilfling, Florian )
  - Integrated Research Training Group on Molecular and Cellular Mechanisms of Neural Homoeostasis
    (Project Heads Acker-Palmer, Amparo ; Luhmann, Heiko J. ; Mittmann, Thomas )
  - Molecular mechanisms regulating homeostatic changes at dendrites and dendritic spines: role of the neurovascular interface
    (Project Head Acker-Palmer, Amparo )
  - Neurovascular signals controlling CNS barrier homeostasis in response to damage
    (Project Heads Acker-Palmer, Amparo ; Segarra, Marta )
  - Pericytes and perivascular fibroblasts in the control of cerebral damage
    (Project Head Hefendehl, Jasmin Kim )
  - Pexophagy and mitophagy in cellular homeostasis, aging and disease
    (Project Heads Bremm, Anja ; Eimer, Stefan )
  - SFB 1080: Molecular and Cellular Mechanisms of Neural Homeostasis
    (Spokespersons Acker-Palmer, Amparo ; Nitsch, Robert )
- Completed projects
  - Central imaging facility for advanced light and correlated light and electron microscopy
    (Project Heads Eimer, Stefan ; Nitschke, Roland )
  - Das Armadillo Repeat Protein ARVCF als Interaktionspartner von Cadherin-Catenin-Komplexen: Funktion und Regulation
    (Project Head Starzinski-Powitz, Anna )
  - Der Mechanismus von Exo- und Endocytose bei der induzierten Sekretion von Signalstoffen aus kultivierten Astrocyten
    (Project Heads Volknandt, Walter ; Zimmermann, Herbert )
  - Die Expression von Ekto-Nukleotidasen in neuronalem Gewebe: Biochemische, molekulare und funktionelle Charakterisierung
    (Project Heads Braun, Norbert ; Zimmermann, Herbert )
  - Differential Partners and Dynamics of Membrane Protein Shrew-1 in Polarized and Non-Polarized Cells
    (Project Head Starzinski-Powitz, Anna )
  - Dissecting molecular pathways to resilience: the role of DRR1
    (Project Heads Acker-Palmer, Amparo ; Müller, Marianne )
  - Dissecting the regulatory mechanisms of alternative polyadenylation and nuclear retention of mRNAs by SR proteins
    (Project Heads Müller-McNicoll, Michaela ; Zarnack, Katharina )
  - Funkctional Dynamics of Shrew-1 in Epithelial Adherens Junctions
    (Project Head Starzinski-Powitz, Anna )
  - Integrated Research Training Group
    (Project Heads Göringer, H. Ulrich ; Müller-McNicoll, Michaela )
  - Integrated Research Training Group on Control of Cell Motility in Morphogenesis, Cancer Invasion and Metastasis
    (Project Heads Börries, Melanie ; Lecaudey, Virginie )
  - Mechanisms underlying migration directionality in a collectively migrating cell group
    (Project Head Lecaudey, Virginie )
  - Multifunktionalität von Glykolyseenzymen
    (Project Head Bereiter-Hahn, Jürgen )
  - Selective autophagy of mitochondria and peroxisomes in organismic aging and development
    (Project Heads Eimer, Stefan ; Osiewacz, Heinz Dieter )
  - Struktur, Biogenese und Funktion einer neuen Klasse von Speichervesikeln
    (Project Head Bonzelius, Frank )
  - The control of vascular morphogenesis by neuronal guidance cues
    (Project Head Acker-Palmer, Amparo )
  - The Synaptic Vesicle Proteome: Identification and Functional Characterization of Novel Constituents
    (Project Heads Volknandt, Walter ; Zimmermann, Herbert )
  - The Synaptic Vesicle Proteome under conditions of Rest and Activation
    (Project Heads Volknandt, Walter ; Zimmermann, Herbert )
Major Research Instrumentation
- Completed projects
CRC/Transregios
- Current projects
  - The role of arcRNAs and nuclear condensate dynamics in the splicing response to hypoxia
    (Project Heads Müller-McNicoll, Michaela ; Zarnack, Katharina )
Research Training Groups
- Current projects
  - GRK 2566: Interfacing image analysis and molecular life-science (Imol)
    (Spokesperson Frangakis, Achilleas )
- Completed projects
  - GRK 361: Neural Plasticity: Molecules, Structures, Functions
    (Spokesperson Zimmermann, Herbert )
Clusters of Excellence
- Completed projects
  - EXC 115: Macromolecular Complexes
    (Spokespersons Dötsch, Volker ; Schwalbe, Harald )
  - EXC 147: Cardio-Pulmonary System
    (Spokespersons Dimmeler, Stefanie ; Seeger, Werner ; Zeiher, Andreas Michael )
  - EXC 294: Centre for Biological Signalling Studies (bioss) - From Analysis to Synthesis
    (Spokesperson Reth, Michael )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 2026: Cardio-Pulmonary Institute (CPI)
    (Spokespersons Dimmeler, Stefanie ; Seeger, Werner )

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