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Institution
Universität zu Lübeck
Sektion Naturwissenschaften
Institut für Biochemie
Address
Ratzeburger Allee 160
23562 Lübeck
Deutschland
GERiT
This institution in GERiT
23562 Lübeck
Projects
Priority Programmes
Completed projects
Genetik, Enzymologie und strukturelle Basis der stringenten Stoffwechselkontrolle durch Guanosinpolyphosphate
(Applicant
Hilgenfeld, Rolf
)
Intracellular feeding of Plasmodium parasites: Characterization and inhibition of the interaction between falcipain-2 and hemoglobin
(Applicant
Hilgenfeld, Rolf
)
Struktur und Funktion des soxLN-Komplex von Sulfolobus, das erste archeale Analog des Cytochrom bc1-/ b6f-Komplex
(Applicant
Schmidt, Christian
)
Research Grants
Current projects
Elicitation of antibodies broadly neutralizing the porcine reproductive and respiratory syndrome virus (PRRSV) using reverse vaccinology
(Applicants
Krey, Thomas
;
Lamp, Benjamin
)
Role of Kaposi’s sarcoma-associated herpesvirus complement control protein in cell migration and angiogenesis
(Applicants
Krey, Thomas
;
Viejo-Borbolla, Abel
)
Completed projects
Development of germline-targeting HCV E2 immunogens to drive neutralizing antibody evolution
(Applicants
Krey, Thomas
;
Pietschmann, Thomas
)
Development of recombinant ELISA for diagnosis of Lassa fever in Africa and structural and biochemical characterisation of the replication complex of Lassa virus
(Applicants
Günther, Stephan
;
Hilgenfeld, Rolf
)
Entwicklung von Inhibitoren der coronaviralen Hauptprotease als neue antivirale Wirkstoffe gegen SARS (Schweres Aktues Atemwegssyndrom) und andere Coronavirusinfektionen
(Applicant
Hilgenfeld, Rolf
)
Grundlagen des Eisentransports und -stoffwechsels bei Archaebakterien
(Applicant
Matzanke-Markstein, Berthold F.
)
Kdo-Aktivierung und -Transfer in A. aeolicus
(Applicant
Mesters, Jeroen
)
Mip-Proteine als bakterielle Virulenzfaktoren: Mechanismen und Strukturen multifunktioneller Komplexe mit Naturstoffen und Wirtszell-Proteinen
(Applicant
Hilgenfeld, Rolf
)
Role of the human cytomegalovirus UL77 protein in capsid assembly and maturation
(Applicants
Borst, Eva Maria
;
Krey, Thomas
)
Structural and functional characterization of the chemokine enhancing activity of varicella zoster virus (VZV) glycoprotein C
(Applicants
Krey, Thomas
;
Viejo-Borbolla, Abel
)
Structure-based design of an epitope-focused Hepatitis C virus vaccine
(Applicants
Krey, Thomas
;
Pietschmann, Thomas
)
The tail-specific protease (Tsp) of Chlamydiae spp.: Mechanistic and structural characterization of its interactions with host-cell proteins
(Applicant
Hansen, Guido
)
Clinical Research Units
Completed projects
Viral-gestörter zerebraler Metabolismus
(Applicant
Mesters, Jeroen
)
Research Units
Current projects
FOR 2799: Receiving and Translating Signals via the gamma-delta T Cell Receptor
(Spokesperson
Prinz, Immo
)
Structural characterization of γδ-TCR-ligand interaction
(Applicant
Krey, Thomas
)
Research Fellowships
Completed projects
Towards a mechanistic model of herpes simplex virus primary envelopment mediated by the nuclear egress complex
(Applicant
Bigalke, Janna
)
Von der Analyse von SifA/SifB vermittelten Veränderungen in der Vesikel-Reifung von Salmonellen-haltigen Vakuolen hin zu der Analyse weiterer intrazellulärer Pathogene
(Applicant
Deiwick, Jörg
)
Major Research Instrumentation
Completed projects
High throughput Imaging System for analysis of protein crystals
HPLC/ESI-Ionenfallen-Massenspektrometer
Collaborative Research Centres
Completed projects
Internalisierung und Membranfusion von BVDV
(Project Heads
Krey, Thomas
;
Rümenapf, Tillmann Hans
)
Structural flexibility in the Hepatitis C virus glycoprotein complex as viral strategy to evade the humoral immune system
(Project Head
Krey, Thomas
)
Strukturaufklärung multimerer Proteinkomplexe durch Röntgenstrukturanalyse
(Project Head
Hilgenfeld, Rolf
)
Virulenzfaktoren intrazellulärer Pathogene und Signaltransduktion in der infizierten Wirtszelle; Mechanismen und Struturen multifunktioneller Komplexe von Mip-Proteinen mit Naturstoffen und Wirtszell-Proteinen
(Project Head
Hilgenfeld, Rolf
)
Research Training Groups
Current projects
GRK 2887: VISualization and structure in virus infectION (VISION)
(Spokesperson
Krey, Thomas
)
Completed projects
GRK 768: Biomolecular Switches ? Coding of Proteins via Conformational Changes and Posttranslational Modifications
(Spokesperson
Heinemann, Stefan H.
)
Clusters of Excellence
Completed projects
EXC 306: Inflammation at Interfaces
(Spokesperson
Schreiber, Stefan
)
Graduate Schools
Completed projects
GSC 235: Graduate School for Computing in Medicine and Life Sciences
(Spokesperson
Schweikard, Achim
)
Clusters of Excellence (ExStra)
Current projects
EXC 2155: RESIST - Resolving Infection Susceptibility
(Spokespersons
Förster, Reinhold
;
Hansen, Gesine
;
Schulz, Thomas
)
Additional Information
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