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Institution

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Johannes Gutenberg-Universität Mainz
Universitätsmedizin
Institut für Medizinische Mikrobiologie und Hygiene

Address Obere Zahlbacher Straße 67
55131 Mainz
Deutschland

GERiT This institution in GERiT

55131 Mainz

Projects

Emmy Noether International Fellowships
- Completed projects
  - Untersuchung zur Rolle von Nef in der Pathognese der HIV Infektion durch MI/DC- spezifische transgene Mausmodelle
    (Applicant Sparwasser, Tim Dominik )
Priority Programmes
- Completed projects
  - Molekulare Charakterisierung der an der Interaktion zwischen Cryptosporidium parvum und Darmepithelzellen beteiligten Proteine
    (Applicant Petry, Franz )
Research Grants
- Completed projects
Collaborative Research Centres
- Current projects
  - Therapeutic blockade of Regulatory T cells
    (Project Head Sparwasser, Tim Dominik )
- Completed projects
  - Analyse der Invasion von Epithelzellen durch parasitäre Darmprotozoen
    (Project Head Petry, Franz )
  - Beitrag zur Aufklärung der Funktion der DNAJ Chaperone in Tumor Suppression
    (Project Head Kurzik-Dumke, Ursula )
  - Die Bedeutung des "klassischen" und des Mannan-binding lectin-(MBL)-Aktivierungsweges der Komplementkaskade bei bakteriellen Infektionen
    (Project Head Loos, Michael )
  - Die Bedeutung des "klassischen" und des Mennose-binding lectin- (MBL)- Aktivierungsweges der Komplementkaskade bei bakteriellen Infektionen
    (Project Head Loos, Michael )
  - Invasionsmechanismen von Humanpapillomviren
    (Project Heads Sapp, Martin ; Streeck, Rolf Eberhard )
  - In vivo analysis of regulatory T cell (Treg) function during tumorigenesis: immunoregulation via specific manipulation of Tregs and optimized vaccination strategies
    (Project Head Sparwasser, Tim Dominik )
  - Resistance to infections with the intestinal parasite Cryptosporidium parvum
    (Project Head Petry, Franz )
  - Role of regulatory immune cells during allergic airway inflammation
    (Project Head Sparwasser, Tim Dominik )
  - Structure and function of pore-forming toxins
    (Project Heads Husmann, Matthias ; Valeva, Angela )
  - Struktur und Funktion porenbildender Toxine
    (Project Heads Valeva, Angela ; Walev, Iwan )
  - Transkriptionsanalyse in permeabilisierten Zellen
    (Project Heads Bhakdi, Sucharit ; Husmann, Matthias )
  - Understanding innate and regulatory immune mechanisms against mycobacteria to optimize vaccine strategies
    (Project Head Sparwasser, Tim Dominik )
  - Zellbiologische Aspekte porenbildender Toxine
    (Project Heads Bhakdi, Sucharit ; Husmann, Matthias )
CRC/Transregios
- Current projects
  - The role of cAMP in regulatory T cell homeostasis and function
    (Project Head Sparwasser, Tim Dominik )
  - The role of cellular metabolic pathways and the influence of the microbiome in the pathogenesis of psoriasis
    (Project Heads Sparwasser, Tim Dominik ; Vieira-Silva, Ph.D., Sara )
- Completed projects
  - Entwicklung BAC (Bacterial Artificial Chromosome) transgener Mausmodelle zur Analyse der Rolle von Dendritischen Zellen in der Pathogenese des allergischen Astmas
    (Project Head Sparwasser, Tim Dominik )
Research Training Groups
- Completed projects
  - GRK 1441: Regulation of the Allergic Response in Lung and Skin
    (Spokesperson Werfel, Thomas )
International Research Training Groups
- Completed projects
  - GRK 1273: Strategies of Human Pathogens to Establish Acute and Chronic Infections
    (Spokesperson Suerbaum, Sebastian )

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