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Klinikum der Technischen Universität München (TUM Klinikum)
Institut für Klinische Chemie und Pathobiochemie

Address Ismaninger Straße 22
81675 München
Deutschland

GERiT This institution in GERiT

81675 München

Projects

Research Grants
- Current projects
- Completed projects
Research Units
- Current projects
  - Coordination Funds
    (Applicant Jellusova, Julia )
  - FOR 5560: Crosstalk between B cell metabolism and signaling
    (Spokesperson Jellusova, Julia )
  - MALT1 signaling network in B cell metabolism and function
    (Applicants Ruland, Jürgen ; Strittmatter, Ph.D., Nicole )
  - Mitochondrial Ca2+ in B cell signaling and metabolism
    (Applicant Jellusova, Julia )
  - Targetable metabolic dependencies in CLL
    (Applicants Buchner, Maike ; Eichner, Ph.D., Ruth )
Collaborative Research Centres
- Current projects
  - Impact of microbiome-derived metabolites on innate immunity, immune function and tissue homeostasis in graft-versus-host disease
    (Project Heads Poeck, Hendrik ; Ruland, Jürgen )
  - Mechanismen der CBM-Signalübertragung in regulatorischen T-Zellen
    (Project Head Ruland, Jürgen )
- Completed projects
  - Aberrant Immune Receptor Signalling in T-cell lymphoma
    (Project Head Ruland, Jürgen )
  - Card9 Signaling in the innate immune response
    (Project Head Ruland, Jürgen )
  - Central Tasks
    (Project Head Ruland, Jürgen )
  - Immune cell signalling during the transformation of CLL to Richter Syndrome
    (Project Head Buchner, Maike )
  - MALT1 Signaling in lymhomagenesis
    (Project Head Ruland, Jürgen )
  - Mechanisms of aberrant NF-kappaB Activation in Diffuse Large B Cell Lymphoma
    (Project Head Ruland, Jürgen )
  - Mechanisms of inflammatory BCL10 signalling in intestinal carcinogenesis
    (Project Heads Ruland, Jürgen ; Schraml-Schotta, Ph.D., Barbara )
  - SFB 1335: Aberrant Immune Signals in Cancer
    (Spokesperson Ruland, Jürgen )
  - Signalspezifische NF-KB Aktivierung in Dendritischen Zellen und in NK Zellen
    (Project Head Ruland, Jürgen )
Research Fellowships
- Completed projects
  - Analysis of the domain specific functions of IKK1 and the role of the alternative NFkappaB pathway and IKK1 in germinal center B cells
    (Applicant Jellusova, Julia )
CRC/Transregios
- Current projects
  - Crosstalk of CARD9/BCL10 and STING Signalling in Nucleic Acid Immunity
    (Project Head Ruland, Jürgen )
  - Exploitation of negative regulators of TCR signaling for therapeutic lymphocyte engineering
    (Project Head Ruland, Jürgen )
- Completed projects
  - Functional Characterization of the SET Domain Protein BCL 12 that is deregulated in diffuse large B Cell Lymphoma by an Immunoglobulin Gene Translocation
    (Project Head Ruland, Jürgen )
  - Integration of cell signaling and metabolism in B cells
    (Project Head Jellusova, Julia )
Research Training Groups
- Current projects
  - GRK 2668: Immune Master Switches in Allergies and Autoimmune Diseases
    (Spokesperson Biedermann, Tilo )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 2189: CIBSS - Centre for Integrative Biological Signalling Studies
    (Spokespersons Driever, Wolfgang ; Hunte, Carola ; Kleine-Vehn, Jürgen ; Weber, Wilfried )

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