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Institution
Universitätsklinikum Ulm
Universitäts- und Rehabilitationskliniken Ulm (RKU)
Universitätsklinik für Neurologie
Address
Oberer Eselsberg 45
89081 Ulm
Deutschland
GERiT
This institution in GERiT
89081 Ulm
Projects
Research Fellowships
Completed projects
Mechanismen der Hochregulation der xCT-Untereinheit des Cystin/Glutamat-Antiporters bei Resistenz gegen oxidativen Stress in der neuronalen Zelllinie HT22 und deren Relevanz bei neurodegernativen Erkrankungen
(Applicant
Lewerenz, Jan
)
TDP-43 as a cerebrospinal fluid marker of amyotrophic lateral sclerosis
(Applicant
Brettschneider, Johannes
)
Untersuchungen zur Bedeutung von alpha-Synuclein für die Pathogenese von Morbus Parkinson (PD) an zwei Zellmodellen für A53T alpha-Synuclein Parkinson
(Applicant
Orth, Michael
)
Untersuchung zur Synthese und antiinflammatorischen Wirkung von Cannabinoiden im zentralen Nervensystem der Maus: (1) Zelltypspezifische Expression endogener Cannabinoide und (2) Wirkung von Cannabinoiden auf Mikrogliazellen
(Applicant
Witting, Anke
)
Research Grants
Current projects
Converging disease mechanisms in amyotrophic lateral sclerosis: microRNAs and the Fragile-X protein family
(Applicants
Freischmidt, Axel
;
Roselli, Ph.D., Francesco
)
Cross-frequency coupling analysis in amyotrophic lateral sclerosis as potential biomarker and therapeutic target
(Applicants
Liebscher, Sabine
;
Ludolph, Albert Christian
)
Genetics and Epigenetics of Amyotrophic Lateral Sclerosis in Mongolia, Egypt, Germany and China
(Applicants
Ludolph, Albert Christian
;
Müller, Kathrin
;
Schlesner, Matthias
;
Siebert, Reiner
)
Modify ALS (ModALS): Integration of OMICs and digital biology in mouse and human motor neuron models for fast-track therapeutic innovation
(Applicant
Weishaupt, Jochen
)
Restoration of excitation/inhibition balance to modulate motoneron degeneration in ALS
(Applicant
Roselli, Ph.D., Francesco
)
Uncovering novel causes and modifiers of amyotrophic lateral sclerosis by nuclear and mitochondrial genome sequencing
(Applicants
Großkreutz, Julian
;
Klein, Christine
;
Spielmann, Malte
;
Weishaupt, Jochen
;
Westenberger, Ana
)
Completed projects
Damage to the spinal cord, peripheral, and enteric nervous systems in Parkinson's disease: Correlation of the Lewy pathology with Braak staging
(Applicant
del Tredici-Braak, Kelly Luise
)
Epidemiology of motoneuron diseases in Swabia
(Applicants
Ludolph, Albert Christian
;
Nagel, Gabriele
;
Rothenbacher, Dietrich
)
Extranigrale Schädigungen bei Morbus Parkinson. Korrelation der pathologischen Hirnveränderungen mit dem klinischen Bild
(Applicant
Braak, Heiko
)
Identification and characterisation of disease genes in early onset amyotrophic lateral sclerosis (ALS) by exome sequencing of patient-parent trios
(Applicant
Volk, Alexander
)
Identification of a mouse model for a hereditary form of Parkinson´s disease. Comparative analysis between human and transgenic mice
(Applicant
Gispert-Sánchez, Suzana
)
Kortikale Reorganisation bei Amyotropher Lateralsklerose
(Applicant
Ludolph, Albert Christian
)
Kortikale und subkortikale Reorganisation bei der Amyotrophen Lateralsklerose: Untersuchung kortikaler und subkortikaler Reorganisation und exekutive Funktionen bei Patienten mit neurodegenerativen Erkrankungen
(Applicants
Birbaumer, Niels
;
Ludolph, Albert Christian
)
Multimodal investigation of neuronal circuits involved in execution and inhibition of self determined and externally guided movements in Tourette syndrome
(Applicants
Münchau, Alexander
;
Schnitzler, Alfons
)
Post-synaptic disruption drives motoneuron vulnerability and disease progression in ALS
(Applicants
Böckers, Tobias
;
Roselli, Ph.D., Francesco
)
Serum Response Factor (SRF) regulates motoneuron vulnerability and activity- dependent neuroprotection in Amyotrophic Lateral Sclerosis.
(Applicants
Knöll, Bernd
;
Roselli, Ph.D., Francesco
)
The influence of temporal and spectral stimulus features on the processing of German vowels and complex tones in developmental dyslexia: Behavioural and fMRI experiments
(Applicant
Steinbrink, Claudia
)
Zerebrale Kontrolle motorischer Aspekte der Sprachproduktion
(Applicants
Ackermann, Hermann
;
Dogil, Grzegorz
;
Ziegler, Wolfram
)
Clinical Trials
Current projects
Efficacy, safety and tolerability of ultra-high-caloric, fatty diet (UFD) in amyotrophic lateral sclerosis (LIPCAL-ALS II)
(Applicant
Dorst, Johannes
)
Completed projects
DEcompressive Surgery for the Treatment of Malignant INfarction of the Middle Cerebral ArterY II
(Applicant
Unterberg, Andreas
)
Efficacy, safety and tolerability of high lipid supplementation in amyotrophic lateral sclerosis
(Applicant
Ludolph, Albert Christian
)
Klinische Studien - Vorbereitungskosten
(Applicant
Ludolph, Albert Christian
)
Clinical Research Units
Completed projects
Oxidativer Stress und DNA Reparatur bei der Motoneurondegeneration
(Applicant
Ludolph, Albert Christian
)
WBP Position
Completed projects
The role of synaptic communication between neurons and NG2-glia in the adult brain
(Applicant
Volbracht, Ph.D., Katrin
)
Priority Programmes
Completed projects
Aktivierungsmechanismen und Signaltransduktion von CDK5 bei Regeneration und Überleben retinaler Ganglienzellen
(Applicant
Bähr, Matthias
)
Collaborative Research Centres
Current projects
Circular RNAs modulate neuronal vulnerability, neuroinflammation and regeneration and are affected by TBI comorbidities
(Project Head
Roselli, Ph.D., Francesco
)
Completed projects
Neurotransmission in den Basalganglien - Bezüge zu Erkrankungen des extrapyramidal-motorischen Systems
(Project Heads
Feuerstein, Thomas J.
;
Landwehrmeyer, G. Bernhard
;
Lücking, Carl Herrman
)
Core Facilities
Completed projects
From Molecule to Man: Center for translational Imaging at Ulm University
(Applicant
Rasche, Volker
)
Research Training Groups
Completed projects
GRK 460: Diagnostic and Therapeutic Concepts in Molecular Medicine
(Spokesperson
Lehmann-Horn, Frank
)
GRK 1789: Cellular and Molecular Mechanisms in Aging (CEMMA)
(Spokesperson
Geiger, Hartmut
)
Additional Information
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