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Institution
Rheinische Friedrich-Wilhelms-Universität Bonn
Medizinische Fakultät
Medizinische Klinik III - Innere Medizin
Address
Venusberg-Campus 1
53127 Bonn
Deutschland
GERiT
This institution in GERiT
53127 Bonn
Projects
Research Grants
Current projects
Contribution of genetic risk variation in G-quadruplex regions to COVID-19 and other complex genetics traits
(Applicants
Ludwig, Kerstin
;
Paeschke, Katrin
)
Defining the role of CD8+ regulatory T cells in Graft-versus-Host Disease after allogeneic stem cell transplantation.
(Applicant
Holderried, Tobias
)
Dissecting the function of LAG-3 in T follicular helper cells in cancer and cancer immunotherapy
(Applicant
Baumjohann, Dirk
)
Elucidating the role of genome instability in dendritic cells
(Applicants
Kiermaier, Eva
;
Paeschke, Katrin
)
Completed projects
Bedeutung der gleichzeitigen Modifikation von Caspase-3 und p21 Cip1/Waf1 Expression für die Regulation hämatopoetischer Stammzellen
(Applicant
Janzen, Viktor
)
Bedeutung des Transkriptionsfaktors Zinc Finger Homeobox 1b (Zfhx1b) für die Regulation hämatopoetischer Stammzellen
(Applicant
Janzen, Viktor
)
Identifizierung und Charaktersisierung von neuen Leukämie assoziierten Tumorantigenen
(Applicant
Brossart, Peter
)
Induktion von CLL-spezifischen T-Zellantworten und Charakterisierung von neuen CLL assoziierten Tumorantigenen
(Applicant
Brossart, Peter
)
Molekulare und funktionelle Untersuchungen zur Differenzierung und Funktion humaner dendritscher Zellen
(Applicant
Grünebach, Frank
)
Regulation of systemic lupus via ICOS triggering by mononuclear phagocytes and B cells
(Applicant
Teichmann, Lino Lars
)
Role of EMT Mediators in Differentiation of Hematopoietic Stem Cells and Interaction with the Microenvironment
(Applicant
Janzen, Viktor
)
Role of the adaptor protein disabled-2 in cytokine signeling of hematopoictic cells
(Applicant
Carstanjen, Dirk
)
Independent Junior Research Groups
Completed projects
Functional analysis of G-quadruplex structures and telomerase activity for DNA double strand break formation and their impact on genome integrity
(Applicant
Paeschke, Katrin
)
The role of T follicular helper cells in T helper cell fate decisions, function, and plasticity
(Applicant
Baumjohann, Dirk
)
Collaborative Research Centres
Current projects
The relevance of helicase activity for genome stability changes within small cell lung cancer
(Project Head
Paeschke, Katrin
)
Completed projects
Dissecting T Cell-Extrinsic Requirements for Early Tfh Cell Differentiation
(Project Head
Baumjohann, Dirk
)
Identifizierung differenziell exprimierter Gene in dendritischen Zellen
(Project Heads
Brossart, Peter
;
Grünebach, Frank
)
Induktion von CLL-spezifischen T-Zellantworten und Charakterisierung neuer CLL-assoziierter Tumorantigene
(Project Head
Brossart, Peter
)
Induktion von CLL-spezifischen T-Zellantworten und Charakterisierung von neuen Cll assoziierten Tumorantigenen
(Project Head
Brossart, Peter
)
Molecular characterization of pathways involved in function and differentiation of human dendritic cells
(Project Head
Brossart, Peter
)
Molekulare und funktionelle Untersuchungen zur Differenzierung und Funktion humaner dendritischer Zellen
(Project Heads
Brossart, Peter
;
Grünebach, Frank
)
Research Fellowships
Completed projects
Mechanistic model of the Rrm3p helicase durin replication through non-nucleosomal protein complexes
(Applicant
Paeschke, Katrin
)
The role of IL-10 and TGF-beta1 secretion by B lymphocytes in lupus prone mice
(Applicant
Teichmann, Lino Lars
)
Major Research Instrumentation
Completed projects
HTP Single Cell Analysis System
CRC/Transregios
Current projects
Recognition and consequences of RNA G4 structures during stress and infection
(Project Head
Paeschke, Katrin
)
Sex hormones in STING-mediated nucleic acid recognition
(Project Heads
Garbi, Natalio
;
Teichmann, Lino Lars
)
Tissue-specific inflammation mechanisms induced by constitutive STING signaling in pediatric autoinflammatory disease with vascular inflammation
(Project Heads
Rösen-Wolff, Angela
;
Teichmann, Lino Lars
)
Research Training Groups
Completed projects
GRK 794: Cellular Mechanisms of Immune-Associated Processes
(Spokesperson
Rammensee, Hans-Georg
)
Clusters of Excellence (ExStra)
Current projects
EXC 2151: ImmunoSensation2 - the immune sensory system
(Spokespersons
Hartmann, Gunther
;
Kolanus, Waldemar
;
Latz, Eicke
;
Schultze, Joachim L.
)
Additional Information
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