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Institution

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Universität Ulm
Institut für Molekulare Medizin

Address Albert-Einstein-Allee 11
89081 Ulm
Deutschland

GERiT This institution in GERiT

89081 Ulm

Projects

Clinical Research Units
- Completed projects
  - Changes in the interaction of aged hematopoietic stem cells with the bone marrow niche/stroma: implications for stem cell aging
    (Applicant Geiger, Hartmut )
  - KFO 142: Molecular and Cellular Aging - From Mechanisms to Clinical Perspectives
    (Spokesperson Scharffetter-Kochanek, Karin )
Research Units
- Current projects
  - FOR 2674: Aging-related epigenetic remodeling in acute myeloid leukemia
    (Spokesperson Lübbert, Ph.D., Michael )
  - Regulation of the histone 4 epigenetic landscape upon hematopoietic stem cell aging
    (Applicant Geiger, Hartmut )
- Completed projects
  - Alterations of H3K9me2 in hematopoietic stem cells: implications for aging and myeloid leukemogenesis
    (Applicant Geiger, Hartmut )
Research Grants
- Current projects
  - Age-related clonal hematopoiesis and its link to age-related changes in the bone marrow microenvironment
    (Applicant Geiger, Hartmut )
  - Aging, hematopoietic stem cells, gene expression and clonality, cell by cell
    (Applicants Geiger, Hartmut ; Mulaw, Ph.D., Medhanie )
- Completed projects
  - Restoring the functionality of the old immune system by rejuvenation of aged hematopoietic stem cells
    (Applicants Geiger, Hartmut ; Schirmbeck, Reinhold )
Collaborative Research Centres
- Current projects
  - Administrative Core: Central Tasks of the CRC
    (Project Head Geiger, Hartmut )
  - Computational Modeling of Hematopoietic Stem Cell Aging
    (Project Heads Geiger, Hartmut ; Kestler, Hans A. )
  - Mechanisms of aging and rejuvenation of human hematopoietic stem cells
    (Project Heads Geiger, Hartmut ; Mulaw, Ph.D., Medhanie )
  - SFB 1506: Aging at Interfaces
    (Spokesperson Geiger, Hartmut )
  - Tissues and animals for aging research – an interdisciplinary approach
    (Project Heads Dallmeier, Ph.D., Dhayana ; Denkinger, Michael ; Geiger, Hartmut ; Liebold, Andreas ; Rothenbacher, Dietrich ; Scharffetter-Kochanek, Karin ; Schrezenmeier, Hubert )
- Completed projects
  - Bioactive peptides in normal and compromised hematopoiesis
    (Project Head Geiger, Hartmut )
  - Die Rolle des Retinoblastom-Tumorsuppressor-Gens in der Zelldifferenzierung im hämatopoetischen System
    (Project Head Geiger, Hartmut )
  - Notch signaling as a novel target of AML/ETO
    (Project Heads Geiger, Hartmut ; Oswald, Franz )
  - The contribution of mechanisms of aging of HSCs to leukemia initiation and progression
    (Project Head Geiger, Hartmut )
  - The role of stem cell circulation in trauma
    (Project Head Geiger, Hartmut )
Major Research Instrumentation
- Completed projects
  - Automatic slide scanning microscope for brightfield and fluorescence microscopy
  - Tisch-Durchflusszytometer
Priority Programmes
- Completed projects
  - Investigation of the role of the nuclear receptor NR4a1 during bone turnover and maintenance of the hematopoietic niche in the bone marrow
    (Applicant Krönke, Gerhard )
Research Training Groups
- Completed projects
  - GRK 1789: Cellular and Molecular Mechanisms in Aging (CEMMA)
    (Spokesperson Geiger, Hartmut )
  - GRK 2254: Heterogeneity and evolution in solid tumors (HEIST): Molecular characterization and therapeutic consequences
    (Spokesperson Seufferlein, Thomas )
Graduate Schools
- Completed projects
  - GSC 270: International Graduate School in Molecular Medicine Ulm
    (Spokesperson Kühl, Michael )

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