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Institution
Johannes Gutenberg-Universität Mainz
Universitätsmedizin
Institut für Pathobiochemie
Address
55099 Mainz
Deutschland
GERiT
This institution in GERiT
55099 Mainz
Projects
Research Fellowships
Completed projects
Die Rolle des Hlow-density lipoprotein receptor-related protein gene (LRP) in der Alzheimer`schen Krankheit
(Applicant
Pietrzik, Claus Ulrich
)
Priority Programmes
Completed projects
Identification and functional characterization of neuroprotective signaling mechanisms and of target genes that mediate the selective resistance of neuronalcells against Alzheimer`s Disease-associated oxidative nerve cell death
(Applicant
Behl, Christian
)
Research Grants
Current projects
Cooperative regulation of neuronal autophagy by Sigma-1-Receptor and Wolfram syndrome-causing Wolframin
(Applicant
Behl, Christian
)
Ovastacin and analysis of the proteolytic network of egg-sperm interaction in mammals
(Applicant
Körschgen, Hagen
)
Completed projects
Corticotropin releasing hormone (CRH) in neuroprotection: molecular and cellular analysis of the neurotrophic acitivities of a stress-related neuropeptide
(Applicant
Behl, Christian
)
Functional role of meprin beta in Alzheimer s disease
(Applicants
Becker-Pauly, Christoph
;
Pietrzik, Claus Ulrich
)
The role of LRP during APP processing
(Applicant
Pietrzik, Claus Ulrich
)
The role of the blood-brain barrier in Alzheimer s disease: Interaction of LRP1 and ABC transporter function
(Applicants
Pahnke, Jens
;
Pietrzik, Claus Ulrich
)
Research Units
Completed projects
Analysis of the detrimental effects of Cnr1-/- mice in an Alzheimer's mouse model and of the interplay between CB1 receptor function and amyloid precursor protein processing
(Applicant
Behl, Christian
)
Investigating the roles of endogenous APP family members in stress signaling and aging
(Applicants
Behl, Christian
;
Kögel, Donat
)
Physiological function of APP dimers: neuronal transport, release and receptor interaction
(Applicants
Kins, Stefan
;
Pietrzik, Claus Ulrich
)
Collaborative Research Centres
Current projects
Integrated Research Training Group (IRTG)
(Project Heads
Behl, Christian
;
Bremm, Anja
;
Dötsch, Volker
;
Pohl, Christian
)
Molecular principles guiding lipid structure and function of autophagosomes
(Project Heads
Bhaskara, Ph.D., Ramachandra M.
;
Kern, Andreas
;
Pohl, Christian
)
Regulation of aggrephagy by co-chaperones and assisting proteins
(Project Heads
Behl, Christian
;
Heilemann, Mike
;
Kaulich, Ph.D., Manuel
)
Completed projects
Functional role of meprin β in Alzheimer’s disease
(Project Heads
Becker-Pauly, Christoph
;
Pietrzik, Claus Ulrich
)
Functional role of the proteasome and autophagic protein degradation system in neuronal homeostasis following traumatic brain injury
(Project Heads
Behl, Christian
;
Engelhard, Kristin
;
Mittmann, Thomas
)
Funkctional Analysis of neuronal estrogen receptor Target Genes
(Project Head
Behl, Christian
)
Stabilization of neuronal protein homeostasis by adaptation of chaperone activity to longterm proteotoxic stress in vivo
(Project Heads
Behl, Christian
;
Clement, Albrecht
)
The role of the protein receptor-mediated endocytosis 8 (RME8) in neuronal homeostasis
(Project Heads
Behl, Christian
;
Clement, Albrecht
)
Research Training Groups
Completed projects
GRK 1044: Developmental and Disease-induced Modifications of the Nervous System
(Spokesperson
Luhmann, Heiko J.
)
Additional Information
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