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Institution
Universitätsklinikum Essen
Institut für Virologie
Address
Hufelandstraße 55
45147 Essen
Deutschland
GERiT
This institution in GERiT
45147 Essen
Projects
Research Grants
Current projects
AntiVir-ID: Investigating the underlying immune signatures impacting coronavirus infection
(Applicants
Pfänder, Stephanie
;
Sutter, Kathrin
)
Chronic/latent viral infections modulate the function of cytotoxic T cells and natural killer cells with antitumor activity
(Applicants
Dittmer, Ulf
;
Paschen, Annette
)
Eliminating the retroviral reservoir: Therapeutic induction of cytotoxic follicular T helper cells that kill infected cells in B cell follicles
(Applicant
Dittmer, Ulf
)
Evaluation of human adenovirus-based vectors for immunization in consideration of seroprevalence, immunogenicity and effects of pre-existing immunity
(Applicant
Bayer, Wibke
)
Impact of rat CMV vXCL1 on the interaction between XCR1+ DC and XCL1-producing cells
(Applicant
Voigt, Sebastian
)
Interconnection of cellular autophagy and endosomal membrane trafficking and its role in hepatitis B virus replication, assembly, and release
(Applicant
Lu, Mengji
)
Promoting Excellence in Medicine: The University Medicine Essen Clinician Scientist Academy (UMEA)
(Applicant
Führer-Sakel, Dagmar
)
Completed projects
Complement and regulatory T cells: The effect of complement on regulatory T cell responses in a mouse retrovirus model.
(Applicant
Dittmer, Ulf
)
Defining the cytotoxic T cell response in COVID-19 patients
(Applicants
Dittmer, Ulf
;
Zelinskyy, Gennadiy
)
Die Rolle von Cytokinen bei der Immunität und Pathogenese von Retrovirusinfektionen
(Applicant
Dittmer, Ulf
)
Die Rolle von Virus-infizierten Dendritischen Zellen bei der Induktion einer Retrovirus-induzierten Immunsuppression
(Applicants
Dittmer, Ulf
;
Grabbe, Stephan
)
Genetically capsid-modified adenovirus vectors as nanoparticle vaccines
(Applicant
Dittmer, Ulf
)
Human cytomegalovirus-mediated modulation of leukemia and its immune control by donor T cell alloreactivity to HLA-DPB1 after hematopoietic stem cell transplantation
(Applicants
Fleischhauer, Katharina
;
Trilling, Mirko
)
Identification and characterization of interferon-gamma-stimulated effector proteins and interferon-gamma-repressed dependency factors effecting cytomegalovirus replication
(Applicant
Trilling, Mirko
)
IFNα subtype-specific susceptibility of HBV in the course of infection
(Applicant
Sutter, Kathrin
)
Inhibition der Interferon-stimulierten Genexpression durch das Terminal-Protein (TP) der Hepadnaviren
(Applicant
Lu, Mengji
)
In vivo Analyse der Bedeutung immunmodulierender und antiviraler Gene bei akuter und chronischer Woodchuck Hepatitis Virus Infektion
(Applicant
Lu, Mengji
)
Recruitment and functional activity of tumor-infiltrating CD8+ cytotoxic T cells and CD4+ regulatory T cells
(Applicant
Dittmer, Ulf
)
The role of inhibitory receptors and their ligands in immune escape from CD8+ T cells and the establishment of chronic virus infection
(Applicant
Zelinskyy, Gennadiy
)
Verbesserung von DNA-Impfstoffen gegen retrovirale Infektionen durch die funktionelle Blockade von regulatorischen T-Zellen
(Applicant
Dittmer, Ulf
)
Verwendung Virusantigen-beladener Dendritischer Zellen zur Prävention und Therapie von Retrovirus-induzierten Leukämien
(Applicant
Dittmer, Ulf
)
Virus-induced regulatory T cells in retroviral infection: new targets for immunotherapy of chronic infectious diseases.
(Applicants
Dittmer, Ulf
;
Gunzer, Matthias
)
Virus-induced regulatory T cells in retroviral infection: new targets for immunotherapy of chronic infectious diseases
(Applicant
Dittmer, Ulf
)
Clinical Trials
Completed projects
Adoptive immunotherapy for Adenovirus associated complications post transplantation
(Applicant
Voigt, Sebastian
)
Klinische Studien - Vorbereitungskosten
(Applicant
Voigt, Sebastian
)
Clinical Research Units
Completed projects
Modeling of the transfer of adoptive immunity to hepatitis B and C virus in liver transplantation
(Applicant
Fiedler, Melanie
)
Transfer of adoptive immunity to hepatitis B virus by liver transplantation
(Applicant
Fiedler, Melanie
)
CRC/Transregios
Completed projects
Die Rolle von inhibitorischen Rezeptoren und deren Liganden bei der Immunflucht vor zytotoxischen CD8+ T-Zellen und bei der Etablierung einer chronischen Virusinfektion
(Project Head
Zelinskyy, Gennadiy
)
Modulierung spezifischer T Zellantworten gegen das Hepatitis B Virus (HBV) durch PRRs (TLR2 und -13) und PRR Detektion der HBV Infektion
(Project Heads
Kirschning, Carsten Jürgen
;
Lu, Mengji
)
TRR 60: Mutual Interaction of Viruses with Cells of the Immune System: From Fundamental Research to Immunotherapy and Vaccination
(Spokespersons
Dittmer, Ulf
;
Roggendorf, Michael
)
Virale Zweckentfremdung des Proteins DDB1 als Evasionsstrategie gegen angeborene Immunität
(Project Heads
Le-Trilling, Vu Thuy Khanh
;
Trilling, Mirko
)
Virus-induzierte regulatorische T Zellen in retroviralen Infektionen: Neue Ziele für die Immuntherapie von chronischen Infektionen
(Project Heads
Bayer, Wibke
;
Dittmer, Ulf
;
Gunzer, Matthias
;
Zelinskyy, Gennadiy
)
Zentrales Verwaltungsprojekt
(Project Heads
Dittmer, Ulf
;
Roggendorf, Michael
;
Yang, Dongliang
)
Priority Programmes
Completed projects
Regulation of the induction of IFNα subtypes during HIV infection
(Applicants
Dittmer, Ulf
;
Sitek, Barbara
;
Sutter, Kathrin
)
Research Fellowships
Completed projects
Metabolic regulation of Natural Killer cells' anti-viral responses
(Applicant
Littwitz-Salomon, Elisabeth
)
Major Research Instrumentation
Completed projects
Polychromatischer Durchflusszytometer
Research Training Groups
Completed projects
GRK 1045: Modulation of Host Cell Functions to Treat Viral and Bacterial Infections
(Spokesperson
Dittmer, Ulf
)
GRK 1949: Immune Response in Infectious Diseases - Regulation between Innate and Adaptive Immunity
(Spokesperson
Westendorf, Astrid M.
)
Additional Information
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