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Institution
Rheinische Friedrich-Wilhelms-Universität Bonn
LIMES-Institut
Abteilung für Chemische Biologie
c/o Kekulé-Institut für organische Chemie
Address
Gerhard-Domagk-Straße 1
53121 Bonn
Deutschland
GERiT
This institution in GERiT
53121 Bonn
Projects
Research Grants
Completed projects
Cellular mechanisms of the swimming behaviour of sperms
(Applicant
Kaupp, Ulrich Benjamin
)
Entwicklung eines automatisierten, zeitaufgelösten High-throughput-Screening Assays zur Quantifizierung von Transkriptionsraten in vitro
(Applicant
Famulok, Michael
)
In vitro und in vivo genetische Analyse der fdhF mRNA-Bindungsstellen des Elongationsfaktors SelB durch in vitro Selektion
(Applicant
Famulok, Michael
)
Kissing-loop Interactions as Struts for Higher Order DNA Nanoarchitectures
(Applicant
Famulok, Michael
)
Molekulare und funktionelle Charakterisierung von HCN-Ionenkanälen
(Applicant
Kaupp, Ulrich Benjamin
)
Novel Classes of Photoresponsive DNA Aptamers
(Applicant
Famulok, Michael
)
SYNAPTA - Encoded synthesis, replication and evolution of unnatural nucleic acid therapeutics
(Applicant
Famulok, Michael
)
The function of cAMP and Ca2+ in motility of human sperm
(Applicant
Kaupp, Ulrich Benjamin
)
Research Units
Completed projects
FOR 450: Molecular Physiology of Ion Channels: Between Three-Dimensional Structure and Cellular Function
(Spokesperson
Fahlke, Christoph
)
In vitro-Selektion und in vivo-Expression von Aptameren zur Analyse der molekularen Mechanismen der Zell/Zell-Kommunikation bei Drosophila und anderen zellulären Systemen
(Applicant
Famulok, Michael
)
Structural studies on CNG channels
(Applicant
Kaupp, Ulrich Benjamin
)
Strukturelle Aufklärung von Aptamer/Proteinkomplexen durch membrangebundene Peptid-Repertoires
(Applicant
Famulok, Michael
)
Priority Programmes
Completed projects
Biological microswimmers: From signaling to 3D beat to 3D swimming.
(Applicant
Kaupp, Ulrich Benjamin
)
In vitro selection of enzymes by mRNA-Display
(Applicant
Famulok, Michael
)
Organisation und Funktion eines Transduktions-Komplexes in Sehstäbchen
(Applicant
Kaupp, Ulrich Benjamin
)
SPP 1025: Molekulare Sinnesphysiologie
(Spokesperson
Kaupp, Ulrich Benjamin
)
Reinhart Koselleck Projects
Current projects
Gating of ion channels and shutdown of G-protein-coupled receptors revealed by kinetic DEER spectroscopy.
(Applicant
Kaupp, Ulrich Benjamin
)
Collaborative Research Centres
Completed projects
Aptamer Technologies
(Project Heads
Famulok, Michael
;
Kaupp, Ulrich Benjamin
;
Mayer, Günter
)
Aufbau von höher geordneten DNA-Architekturen durch funktionalisierte DNA
(Project Head
Famulok, Michael
)
Functional analysis of cytohesin-mediated membrane receptor tyrosine kinase signaling
(Project Head
Famulok, Michael
)
Investigating the immunological function of cytohesins with small molecule inhibitors and chemical genomics
(Project Head
Famulok, Michael
)
Mechanism of non-genomic progesterone signalling in human sperm
(Project Heads
Kaupp, Ulrich Benjamin
;
Strünker, Timo
)
Phänotypische Charakterisierung von Signaltransduktions-kaskaden mittels intrazellulärer Aptamere (Intramere)
(Project Head
Famulok, Michael
)
Site-selective incorporation of spin-labels into long functional oligonucleotides
(Project Head
Famulok, Michael
)
Major Instrumentation Initiatives
Completed projects
Fast imaging of integrin-dependent cytoplasmic signaling in adhesion regulation and actin cytoskeletal remodelling events contributing to immune cell migration (HighLight 2004)
(Applicant
Kolanus, Waldemar
)
Research Training Groups
Completed projects
GRK 804: Analysis of Cellular Functions by Combinatorial Chemistry and Biochemistry
(Spokesperson
Famulok, Michael
)
Clusters of Excellence
Completed projects
EXC 1023: ImmunoSensation: The Immune Sensory System
(Spokesperson
Hartmann, Gunther
)
Additional Information
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