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Institution
Universitätsklinikum Schleswig-Holstein
Campus Kiel
Klinik für Kinder- und Jugendmedizin I
Address
Arnold-Heller-Straße 3
24105 Kiel
Deutschland
GERiT
This institution in GERiT
24105 Kiel
Projects
Clinical Research Units
Current projects
Defining outcome signatures of ALL across age groups and genetic subtypes
(Applicants
Baldus, Claudia
;
Cario, Gunnar
)
KFO 5010: CATCH ALL Towards a Cure for Adults and Children with Acute Lymphoblastic Leukemia (ALL)
(Spokesperson
Baldus, Claudia
)
Molecular guided experimental treatments in patients with relapsed/ refractory lymphoid malignancies
(Applicants
Neumann, Martin
;
Schrappe, Martin
)
Completed projects
Charakterisierung von PBMC (peripheral blood mononuclear cells) als minimalinvasives Modell der individuellen Androgenrezeptorfunktion bei Androgenresistenz
(Applicant
Holterhus, Paul-Martin
)
Genotyp-Phänotyp-Korrelation der Androgenresistenz durch Expressionsanalyse androgenregulierter Gene in Genitalhautfibroblasten per cDNA-Microarray
(Applicant
Holterhus, Paul-Martin
)
KFO 111: Intersexualität - vom Gen zur Geschlechtsidentität
(Spokesperson
Hiort, Olaf
)
Research Grants
Current projects
Downstream of the “Androgen receptor-bottleneck”: the transcriptional and chromatin landscape of urogenital midline fusion at single cell resolution and its relevance to differences of sex development (DSD)
(Applicants
Holterhus, Paul-Martin
;
Spielmann, Malte
)
Identification of clinically relevant epigenomic events in pediatric acute lymphoblastic leukemia
(Applicants
Bergmann, Anke Katharina
;
Hoffmann, Steve
)
Completed projects
Androgen Insensitivity Without Androgenreceptor Mutations: from functional studies to the epigenotype
(Applicants
Ammerpohl, Ole
;
Holterhus, Paul-Martin
)
Charakterisierung von PBMC (peripheral blood mononuclear cells) als minimalinvasives Modell der individuellen Androgenrezeptorfunktion bei Androgenresistenz
(Applicant
Holterhus, Paul-Martin
)
Genotyp-Phänotyp-Korrelation der Androgenresistenz durch Expressionsanalyse androgenregulierter Gene in Genitalhautfibroblasten per cDNA-Microarray
(Applicant
Holterhus, Paul-Martin
)
Identification of highly selective co-regulators of the androgen receptor based on a functional in vitro model of androgen insensitivity
(Applicant
Hornig, Nadine
)
Research Fellowships
Completed projects
Experimental study of the effect of combined elastase inhibition and angiotensin-2-receptor blockade on ventilator-induced neonatal lung injury in newborn mice
(Applicant
Preuß, Stefanie
)
Identification of androgen-regulated genes in normal and androgen-intensitive human genital skin fibroblasts by cDNA microarrays
(Applicant
Holterhus, Paul-Martin
)
Major Research Instrumentation
Completed projects
Liquid-Chromatography-Tandem Mass Spectrometer (LC-MS/MS)
Collaborative Research Centres
Current projects
The atlas of steroid hormones in human genital tissues by simultaneous determination of the delta-5, alternative, backdoor and 11-oxygenated C-19 metabolites
(Project Heads
Holterhus, Paul-Martin
;
Kulle, Alexandra
)
The single cell transcriptional and chromatin landscape of sex differentiation and the role of the androgen pathway in extra-genital somatic tissues
(Project Heads
Holterhus, Paul-Martin
;
Spielmann, Malte
)
Additional Information
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