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Project Details

Institution

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Universitätsklinikum Jena
Center for Sepsis Control and Care (CSCC)

Address Am Klinikum 1
07747 Jena
Deutschland

GERiT This institution in GERiT

07747 Jena

Projects

Research Units
- Completed projects
  - Heme and heme degradation products as effectors of hepatic perfusion and excretion failure
    (Applicant Bauer, Michael )
Research Grants
- Completed projects
  - Control of macrophage repolarization and regulation of liver inflammation by HIF-1alpha and STAT3
    (Applicants Löffler, Bettina ; Mosig, Alexander )
  - Regional differences in severe sepsis epidemiology and treatment in Germany
    (Applicant Fleischmann-Struzek, Carolin )
CRC/Transregios
- Current projects
  - Impact of Candida albicans colonization, dietary factors and B-cells for systemic candidiasis
    (Project Heads Bauer, Michael ; Jacobsen, Ilse Denise ; Jungnickel, Berit )
Core Facilities
- Completed projects
  - Jena Biophotonic and Imaging Laboratory
    (Applicants Bauer, Michael ; von Eggeling, Ferdinand ; Popp, Jürgen )
Clinical Trials
- Completed projects
  - A Randomized Controlled Multicenter Trial on Albumin Replacement In Septic Shock (ARISS)
    (Applicant Bauer, Michael )
Collaborative Research Centres
- Current projects
  - Biophotonic characterisation of the interaction of nanoparticles and drugs with hepatic stellate cells
    (Project Heads Bauer, Michael ; Popp, Jürgen ; Schubert, Stephanie )
  - Mimicking viral entry mechanisms with polymeric nanoparticles
    (Project Heads Bauer, Michael ; Eggeling, Christian ; Schubert, Ulrich S. )
  - Prevention of late phase liver damage by targeted modulation of the liver’s immune response
    (Project Heads Bauer, Michael ; Schubert, Ulrich S. ; Waskow, Claudia )
  - Targetable nanoparticles for efficient translocation across gastrointestinal barriers
    (Project Heads Brendel, Johannes ; Mosig, Alexander ; Stallmach, Andreas )
  - Targeting renal phosphoinositide 3-kinase γ (PI3Kγ) by dye-tagged nanoparticles
    (Project Heads Bauer, Michael ; Coldewey, Ph.D., Sina Maren ; Schubert, Ulrich S. )
- Completed projects
  - Selective targeting of hepatocytes using multifunctional block copolymer micelles to restore critical cellular signaling functions
    (Project Heads Bauer, Michael ; Qualmann, Britta ; Schacher, Felix H. )
Priority Programmes
- Current projects
  - Biomechanics of the Platyhelminth Adhesion, Locomotion, and Reproduction
    (Applicants Grevelding, Christoph G. ; Häberlein, Simone ; Mosig, Alexander ; Schacher, Felix H. )
Research Training Groups
- Completed projects
  - GRK 1715: Molecular Signatures of Adaptive Stress Responses
    (Spokespersons Heinzel, Thorsten ; Wetzker, Reinhard )
Graduate Schools
- Completed projects
  - GSC 214: Jena School for Microbial Communication (JSMC)
    (Spokesperson Brakhage, Axel )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 2051: Balance of the Microverse
    (Spokespersons Brakhage, Axel ; Küsel, Kirsten )

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