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Institution
Universitätsklinikum des Saarlandes
Experimentelle und Klinische Pharmakologie und Toxikologie
Address
Kirrberger Straße
66424 Homburg
Deutschland
GERiT
This institution in GERiT
66424 Homburg
Projects
Priority Programmes
Completed projects
Charakterisierung präsynaptischer Ca2+-Kanäle mit Hilfe transgener Mausmodelle
(Applicant
Flockerzi, Veit
)
Neuronal mechanisms of pheromone sensing
(Applicants
Boehm, Ulrich
;
Leinders-Zufall, Trese
)
Research Grants
Current projects
Influence of the TRPV6 ion channel on calcium-dependent processes in the female reproductive tract and the fetal yolk sac
(Applicants
Fecher-Trost, Claudia
;
Weißgerber, Petra
)
Completed projects
Der calciumabhängige Ionenkanal TRPV6 Identifizierung der Kanal-Untereinheit und von damit assozierten Proteinen
(Applicant
Fecher-Trost, Claudia
)
Functional analysis of prolactin-sensitive neural circuits in the arcuate nucleus.
(Applicant
Boehm, Ulrich
)
Functional characterization of GnRH receptor neurons and their neural circuitry in the mouse brain
(Applicant
Boehm, Ulrich
)
Functional characterization of Gpr120 expressing cells and their role in fatty acid detection in knock-in mouse models
(Applicant
Boehm, Ulrich
)
Functional characterization of neural circuits controling puberty in female mice
(Applicant
Boehm, Ulrich
)
Functional role of TET-dependent DNA demethylation in reproduction and hormone-dependent cancers.
(Applicant
Boehm, Ulrich
)
Wirkt die CaVbeta3-Untereinheit protektiv bei chronisch entzündlichen ZNS-Erkrankungen?
(Applicants
Diem, Ricarda
;
Flockerzi, Veit
)
Collaborative Research Centres
Completed projects
Ca2+ channels in micro- and macroglial cells
(Project Heads
Beck, Andreas
;
Flockerzi, Veit
)
Ca2+ signal generation in gonadotropes
(Project Head
Boehm, Ulrich
)
Cavβ2- and Cavβ3-specific signal transduction
(Project Heads
Belkacemi, Anouar
;
Flockerzi, Veit
;
Philipp, Stephan E.
)
Central Tasks of the Collaborative Research Center
(Project Heads
Flockerzi, Veit
;
Rettig, Jens
)
Definierte Mutanten
(Project Head
Flockerzi, Veit
)
Funktion von TRPC4- und TRPM3-Kanälen in der Maus
(Project Heads
Cavalié, Adolfo
;
Philipp, Stephan E.
)
Mechanisms and regulation of Ca2+ leakage from the ER
(Project Heads
Cavalié, Adolfo
;
Lang, Sven
;
Zimmermann, Richard
)
SFB 530: Spatio-Temporal Interactions of Cellular Signalling Molecules
(Spokesperson
Flockerzi, Veit
)
SFB 894: Ca2+-Signalling: Molecular Mechanisms and Integrative Functions
(Spokespersons
Flockerzi, Veit
;
Rettig, Jens
)
Subunits of Ca 2+-selective cation channels
(Project Head
Flockerzi, Veit
)
Transgenic technologies
(Project Heads
Boehm, Ulrich
;
Weißgerber, Petra
)
Zentrales Verwaltungsprojekt
(Project Head
Flockerzi, Veit
)
Emmy Noether International Fellowships
Completed projects
Tracing neural circuitry: The pheromone code (Analyse der neuronalen Kodierung von Pheromonen und der Verschaltung der Sinnenszellen des Vomeronasalorgans mit höhreren Zentren in der Maus
(Applicant
Boehm, Ulrich
)
Research Fellowships
Completed projects
Nachweis und Eigenschaft neuronaler und glialer TRP-Kanäle im zentralen Nervensystem der Maus in situ
(Applicant
Beck, Andreas
)
Clinical Research Units
Completed projects
Rolle von TRP-Kanälen beim kardialen Remodelling
(Applicant
Freichel, Marc
)
Major Research Instrumentation
Completed projects
Fluoreszenz-Imagingsystem
Hochauflösendes Massenspektrometer mit nano-LC und micro-LC Kopplung
Hochauflösendes Massenspektrometer mit nano-LC und micro-LC Kopplung
Live Cell Konfokal Imagingsystem (kombiniert mit Optogenetik)
System für das automatisierte Scannen von Objektträgern mit Fluoreszenz in hohem Durchsatz
Zellsorter
CRC/Transregios
Current projects
The trp zoo: a combinatorial genetic approach to visualize and manipulate TRP-expressing cells
(Project Heads
Boehm, Ulrich
;
Flockerzi, Veit
)
Windows into the brain: Genetic analyses of TRP-channel function(s) in the homeostasis control center
(Project Head
Boehm, Ulrich
)
Completed projects
Physiological function of the TRPV6 protein in placenta
(Project Heads
Fecher-Trost, Claudia
;
Weißgerber, Petra
)
TRPC1 function in Ca2+ homeostasis
(Project Head
Flockerzi, Veit
)
Research Units
Completed projects
Does Cavβ3 subunit confer neuroprotection in chronic inflammatory CNS disease?
(Applicants
Diem, Ricarda
;
Flockerzi, Veit
)
FOR 2289: Calcium homeostasis in neuroinflammation and -degeneration: New targets for therapy of multiple sclerosis?
(Spokesperson
Diem, Ricarda
)
Research Training Groups
Completed projects
GRK 377: Cellular Regulation and Growth
(Spokesperson
Montenarh, Mathias
)
GRK 845: Molecular, Physiological and Pharmacological Analysis of Cellular Membrane Transport
(Spokespersons
Neuhaus, Ekkehard
;
Zimmermann, Richard
)
GRK 1326: Calcium-Signalling and Cellular Nanodomains
(Spokesperson
Bruns, Dieter
)
International Research Training Groups
Completed projects
GRK 1830: Complex Membrane Proteins in Cellular Development and Disease
(Spokespersons
Neuhaus, Ekkehard
;
Niemeyer, Ph.D., Barbara Anne
)
Additional Information
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