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Institution
Universitätsklinikum Essen
Klinik für Allgemeinchirurgie, Viszeral-
und Transplantationschirurgie
Address
Hufelandstraße 55
45147 Essen
Deutschland
GERiT
This institution in GERiT
45147 Essen
Projects
Research Grants
Current projects
Ex-situ evaluation of donor kidneys during isolated machine perfusion
(Applicant
Minor, Thomas
)
Completed projects
Hsp90 Blockade als therapeutischer Ansatz zur Modulation von Tumormetabolismus und -angiogenese gastrointestinaler Karzinome
(Applicant
Lang, Sven Arke
)
Klinische Evaluation der nachträglichen Revitalisierung hypotherm-ischämisch gelagerter Spenderlebern durch Sauerstoffpersufflation
(Applicant
Minor, Thomas
)
Kontrollierte oxygenierte Wiederaufwärmung nach kalter Lagerung und ihr Einfluss auf die Transplantatfrühfunktion unter der anschließenden Reperfusion
(Applicant
Minor, Thomas
)
Präklinische Evaluierung experimenteller Ansätze zur Verbesserung der Organprotektion im Rahmen der Konservierung vorgeschädigter Spenderlebern
(Applicant
Minor, Thomas
)
Reduzierung hypotherm-ischämischer Gewebealterationen durch dopaminerge Stimulation in der Leberkonservierung
(Applicant
Minor, Thomas
)
The role of polo-like kinases1/2 as mediators of hedgehog survival signaling in cholangiocarcinoma cells
(Applicant
Fingas, Christian Dominik
)
Tierexperimentelle Untersuchungen zur Revitalisierung von Spendernieren mittels Sauerstoffpersufflation nach warmischämischer Schädigung durch Kreislaufstillstand
(Applicant
Paul, Andreas
)
Clinical Trials
Completed projects
Machine perfusion preservation vs. simple cold storage of cadaveric kidneys for transplantation
(Applicant
Treckmann, Jürgen
)
Clinical Research Units
Completed projects
Characterization of a hepatocellular carcinoma risk genotype serving as a predictor of recurrence after living donor liver transplantation and its relation to the modulated host milieu observed in the regeneration liver graft
(Applicant
Weber, Frank
)
Heat-shock protein 90 (Hsp90) blockade as a therapeutic approach for modulating tumor metabolism and angiogenesis in cancer
(Applicant
Lang, Sven Arke
)
Steatosis and Living Donor Liver Transplantation: Which Role for Cellular FLICE-inhibitory Protein, Death Ligands, and Fatty Acid Transporters
(Applicant
Canbay, Ali
)
Verbesserung der Dünndarmtransplantation durch Modifikation der Organkonservierung
(Applicant
Tolba, René H.
)
Research Fellowships
Completed projects
Comparison of competing ex vivo preservation techniques and investigation of the mechanisms of graft recovery during ex-vivo perfusion in marginal kidney grafts
(Applicant
Mazilescu, Laura Ioana
)
In vitro- und in vivo-Untersuchungen zur Rolle des Tumorsuppressorproteins KLF6 im Rahmen der hepatischen Steatose, der Leberzellschädigung und der Entwicklung des hepatozellulären Karzinoms
(Applicant
Kocabayoglu, Peri
)
In vitro- und in vivo-Untersuchungen zur Wiederherstellung der tumorspezifisch blockierten TRAIL-induzierten Apoptose als neuer Ansatz zur Therapie des cholangiozellulären Karzinoms
(Applicant
Fingas, Christian Dominik
)
Liver transplantation in Baboons using 1,3-Galactosyltransferase gene-knockout pigs as donors
(Applicant
Heuer, Ph.D., Matthias
)
Research Units
Completed projects
FOR 2127: Selection and Adaptation during Metastatic Cancer Progression
(Spokesperson
Klein, Christoph
)
Role of hepatic stellate cells in the selection and adaptation of metastasizing cancer cells in the hepatic environment
(Applicants
Hellerbrand, Claus
;
Lang, Sven Arke
)
Collaborative Research Centres
Current projects
Effects of the gut microenvironment on liver during cancer
(Project Heads
Izcue, Ph.D., Ana
;
Neumann, Ulf P.
)
Completed projects
A physiologically-based model of bile acid metabolism
(Project Heads
Blank, Ph.D., Lars
;
Neumann, Ulf P.
;
Trautwein, Christian
)
Microbiota and TLR-Signalling in the Development and Recurrence of intrahepatic Cholangiocarcinoma
(Project Heads
Lüdde, Ph.D., Tom
;
Neumann, Ulf P.
)
Additional Information
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