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Institution
Uniklinik Köln
Herzzentrum
Klinik III für Innere Medizin
Address
Kerpener Straße 62
50937 Köln
Deutschland
GERiT
This institution in GERiT
50937 Köln
Projects
Research Fellowships
Completed projects
Charakterisierung eines Mausmodells mit reduzierter und defizienter Calsequestrin Expression
(Applicant
Frank, Konrad
)
Die Bedeutung regionaler Ca2+ - Konzentrationsunterschiede innerhalb der Herzmuskelzelle für die elektromechanische Kopplung
(Applicant
Reuter, Hannes
)
Die Rolle der K+ -Kanäle in der Entwicklung von Hypertonie und Herzinsuffizienz zu charakterisieren
(Applicant
Zobel, Carsten
)
Funktionelle Bedeutung von Six-transmembrane Proteine of Prostate 2 (STAMP2) im Rahmen der Atherogenese
(Applicant
ten Freyhaus, Henrik
)
Nicotine and miR-24 in abdominal aortic aneurysm
(Applicant
Adam, Matti
)
Regulation der endocytotischen Internalisierung synaptischer GABAa-Rezeptoren durch Ubiquitinierung
(Applicant
Michels, Guido
)
Regulation und funktionelle Bedeutung myokardialer Uncoupling Proteine (UCPs) unter physiologischen und pathophysiologischen Bedingungen
(Applicant
Huntgeburth, Michael
)
Targeting blood stem cell activity and extramedullary monocytopoiesis to treat atherosclerosis
(Applicant
Hoyer, Friedrich Felix
)
Unravelling Treg Plasticity in Atherosclerosis
(Applicant
Winkels, Holger
)
Validierung und Erprobung eines neuartigen dualen MRT / optischen Kontrastmittels zur Stammzellmarkierung in-vivo
(Applicant
Ladage, Dennis Christian
)
Research Grants
Current projects
The impact of infectious disease on cardiovascular leukocyte heterogeneity in mice
(Applicant
Hoyer, Friedrich Felix
)
The Role of Adaptive and Innate Immunity for the Development of Aortic Valve Stenosis
(Applicants
Hoyer, Friedrich Felix
;
Weisheit, Christina Katharina
;
Winkels, Holger
)
The role of myeloperoxidase in inflammatory processes and macrophage activation in heart failure
(Applicant
Mollenhauer, Ph.D., Martin
)
Completed projects
Bedeutung der Interaktion von Myeloperoxidase mit der endothelialen Glykokalyx für die Leukozytenrekrutierung und die Gefäßfunktion
(Applicants
Baldus, Stephan
;
Klinke, Ph.D., Anna
)
Bedeutung neutrophiler Granulozyten bei der Pathogenese der pulmonalen arteriellen Hypertonie
(Applicant
Baldus, Stephan
)
Bedeutung von Myeloperoxidase für die CD11b abhängige Leukozytenmigration
(Applicant
Baldus, Stephan
)
Charakterisierung der Bedeutung PDGF-vermittelter Signaltransduktionswege für die Hypertrophie und Funktion von Kardiomyozyten
(Applicant
Rosenkranz, Stephan
)
Electrical integration, maturation and proarrhythmic risk of induced pluripotent stem cell-derived cardiomyocytes after transplantation in infarcted mouse hearts
(Applicant
Halbach, Marcel
)
Mechanismen und Konsequenz nukleärer Translokation von Myeloperoxidase
(Applicant
Baldus, Stephan
)
Role of mitogen-activated proteinkinases p38MAPK und MKK-1 in modulation of the NF-kB pathway and modulation of histone acetylation following the expression of inflammatory cytokine expression in human alveolar macrophages
(Applicant
Koch, Andrea
)
TGF-ß1 vermittelte Regulation von UCP3 und dessen Rolle bei der Pathogenese der Myokardhypertrophie und Herzinsuffizienz.
(Applicant
Huntgeburth, Michael
)
Major Research Instrumentation
Completed projects
Echokardiographie-System für Kleintiere
CRC/Transregios
Current projects
Biomarkers and mechanisms of disease progression and outcome in aortic stenosis in humans
(Project Heads
Franklin, Bernardo
;
Luetkens, Julian Alexander
;
Mauri, Victor
;
Shamekhi, Jasmin
;
Veulemans, Ph.D., Verena
;
Zeus, Tobias
)
Modification of PI 3-kinase signalling as a therapeutic strategy against aortic aneurysm formation
(Project Head
Rosenkranz, Stephan
)
Necroptosis in aortic aneurysm disease - significance of inflammation in MLKL dependent cell death
(Project Heads
Adam, Matti
;
Garcia Sáez, Ana Jesús
;
Pasparakis, Manolis
)
The impact of nitrated fatty acids in a translational porcine model of abdominal aortic aneurysm
(Project Heads
Mollenhauer, Ph.D., Martin
;
Stei, Marta
;
Wagenhäuser, Markus
)
The role of the olfactory receptor 2 in aortic aneurysm formation
(Project Head
Winkels, Holger
)
Completed projects
Posttranslational modifications in Marfan’s disease mediated by myeloperoxidase
(Project Heads
Baldus, Stephan
;
Winkels, Holger
)
WBP Fellowship
Current projects
Characterization of arrhythmogenic atrial cardiomyopathies
(Applicant
Dittrich, Sebastian
)
Collaborative Research Centres
Completed projects
Funktionelle Bedeutung von Sorcin für die Regulation der myokardialen Ca2+-Homöostase und Kontraktilität
(Project Heads
Bölck, Birgit
;
Frank, Konrad
;
Schwinger, Robert H.G.
)
Importance of class IA PI 3-Kinase isoforms for the pathogenesis of pulmonary hypertension
(Project Head
Rosenkranz, Stephan
)
Clinical Trials
Current projects
Pulmonary Embolism International Thrombolysis Study (PEITHO) Study 3: A reduced dose of intravenous thrombolytic treatment for patients with intermediate high-risk acute pulmonary embolism
(Applicant
Konstantinides, Stavros
)
Research Training Groups
Completed projects
GRK 2407: Inflammatory and cellular stress signaling: Switches to vascular dysfunction
(Spokesperson
Baldus, Stephan
)
Additional Information
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