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Institution
Rheinische Friedrich-Wilhelms-Universität Bonn
Medizinische Fakultät
Institut für Neuropathologie
Address
Venusberg-Campus 1
53127 Bonn
Deutschland
GERiT
This institution in GERiT
53127 Bonn
Projects
Research Fellowships
Completed projects
Isolierung und Charakterisierung von Genen, die durch das Onkogen qin transkriptionell reguliert werden. Untersuchungen zur qin-Promotorstruktur.
(Applicant
Waha, Anke
)
Independent Junior Research Groups
Completed projects
Funktion und Modulation von RIMs und RIM-assoziierten Proteinen im normalen und epileptischen Gehirn
(Applicant
Schoch McGovern, Susanne
)
Research Grants
Current projects
Neuro-aCSis – Bonn Neuroscience Clinician Scientist Program
(Applicant
Petzold, Gabor
)
Optical dissection of glycine and D-serine signalling using newly-developed sensors
(Applicants
Dietrich, Dirk
;
Henneberger, Christian
;
Schoch McGovern, Susanne
)
RIM4 dependent synaptopathy causing a novel form of episodic ataxia: molecular mechanisms and altered circuit function
(Applicants
Dietrich, Dirk
;
Schoch McGovern, Susanne
)
Why it takes time to stay in balance: Defining the molecular timer of homeostatic plasticity and its power to regulate network activity and meta-plasticity
(Applicants
Dietrich, Dirk
;
Schoch McGovern, Susanne
)
Completed projects
Calcium, proliferation and AMPA receptors in NG2 glial cells
(Applicants
Dietrich, Dirk
;
Schoch McGovern, Susanne
)
Epigenetic phatomechanisms promoting epileptogenesis in focal and generallized epilepsies (EpiGENet)
(Applicants
Becker, Albert
;
Blümcke, Ingmar
;
Sander, Thomas
)
Molekulare Pathogenese des Hepatoblastoms
(Applicant
Pietsch, Torsten
)
Presynaptic tethers: molecular composition and functional role
(Applicants
Lucic, Vladan
;
Schoch McGovern, Susanne
;
Stein, Valentin
)
Single-cell transcriptome sequencing to investigate mechanisms of epileptogenesis in genetic mouse models and human brain biopsy tissue
(Applicants
Becker, Albert
;
Hedrich-Klimosch, Ulrike
;
Isbrandt, Dirk
;
Koch, Ph.D., Henner
)
CRC/Transregios
Completed projects
Antiepileptogenic approaches targeting the T-type Ca2+ channel Cav3.2
(Project Heads
Becker, Albert
;
Schoch McGovern, Susanne
;
Yaari, Yoel
)
Epilepsie-induzierter neuronaler Zelltod: der JNK/c-Jun/Bim-Signaltransduktionsweg und Möglichkeiten der Intervention durch intrazellulären Proteintransfer
(Project Head
Frank, Stephan
)
Epilepsy as synaptopathy: Plasticity of the presynaptic release machinery
(Project Heads
Becker, Albert
;
Schoch McGovern, Susanne
)
Collaborative Research Centres
Current projects
Circuit mechanisms of altered excitability in experimental cortical malformations
(Project Heads
Beck, Heinz
;
Schoch McGovern, Susanne
)
Integrated Research Training Group
(Project Heads
Beck, Heinz
;
Schoch McGovern, Susanne
)
Microcircuit mechanisms underlying epileptogenesis and behavioural impairment in anti-Drebrin auto-antibody mediated limbic encephalitis
(Project Heads
Becker, Albert
;
Wenzel, Michael
)
Recombinant adeno-associated- and lentiviral technologies
(Project Heads
Becker, Albert
;
Grömping, Yvonne
;
van Loo, Karen M. J.
;
Schoch McGovern, Susanne
;
Schwarz, Ph.D., Karl Martin
)
Completed projects
Bedeutung von regulatorischer DNA-Methylierung für die Pathogenese von Gliomen
(Project Heads
Waha, Andreas
;
Wiestler, Otmar Dieter
)
Mechanisms of zinc-sensitive metal-regulatory transcription factor 1 induction of hippocampal epileptic network activity
(Project Heads
Becker, Albert
;
van Loo, Karen M. J.
)
Molecular mechanisms underlying synaptic plasticity and tenacity
(Project Heads
Schoch McGovern, Susanne
;
Ziv, Ph.D., Noam
)
Molekulare Pathogenese des Medulloblastoms: Die Rolle des Hedgehog-patched-Signalweges in der Entwicklung und Tumorigenese cerebellärer Progrenitorzellen
(Project Heads
Pietsch, Torsten
;
Wiestler, Otmar Dieter
)
Regulation of membrane trafficking and organization by the Liprin-á protein family
(Project Head
Schoch McGovern, Susanne
)
Clinical Research Units
Completed projects
Mechanisms of microglia-mediated neuronal damage and dysfunction: Role of the "TNFa-Zn2+" cascade
(Applicant
Beck, Heinz
)
Priority Programmes
Completed projects
Heterogeneity of neuron-NG2 glia synapses matches glial response to regionally diverse neuronal firing behavior.
(Applicants
Dietrich, Dirk
;
Schoch McGovern, Susanne
)
Research Units
Current projects
FOR 2715: Epileptogenesis of genetic epilepsies
(Spokesperson
Lerche, Holger
)
Molecular and network mechanisms-derived targeted interventions in neonatal genetic epilepsies
(Applicants
Becker, Albert
;
Isbrandt, Dirk
)
Completed projects
Functional epigenomic dissection of genetic generalized epilepsies
(Applicants
Becker, Albert
;
Sander, Thomas
)
Additional Information
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