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Institution
Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE)
c/o Charité - Universitätsmedizin Berlin
Address
Charitéplatz 1
10117 Berlin
Deutschland
GERiT
This institution in GERiT
10117 Berlin
Projects
Heisenberg Fellowships
Completed projects
Arf6-Aktivierung durch BRAG-Proteine: synaptische Regulation und Rolle bei mentaler Retardierung
(Applicant
Kornau, Hans-Christian
)
Research Grants
Current projects
Identification of the memory signature: gene expression patterns underlying synapse strengthening and weakening
(Applicant
Dean, Camin
)
Molecular Mechanisms Underlying the Interaction between Synapsin, alpha-Synuclein and Synaptic Vesicles
(Applicant
Milovanovic, Dragomir
)
“NMDA receptor hypofunction revisited: Cellular mechanisms of psychosis in mouse models of NMDA receptor ablation”
(Applicants
Liebscher, Sabine
;
Prüß, Harald
)
Rewiring of GABAergic inhibitory cells recruited during spatial representation
(Applicants
Haberl, Matthias
;
Viana da Silva, Ph.D., Silvia
)
Completed projects
Arf6-Aktivierung durch BRAG-Proteine: synaptische Regulation und Rolle bei mentaler Retardierung
(Applicant
Kornau, Hans-Christian
)
Epitopic targets of the monoclonal auto-antibody repertoire in autoimmune encephalitis
(Applicant
Prüß, Harald
)
Immune-mediated pathogenesis and development of autoimmunity in neurological manifestations of COVID-19
(Applicants
Franke, Christiana
;
Prüß, Harald
;
Warnke, Clemens
)
Regulation of dense core vesicle trafficking and capture by synaptotagmin 4
(Applicant
Dean, Camin
)
Regulation of post-synaptic receptor recycling by synaptotagmin 3
(Applicant
Dean, Camin
)
Synaptic autoimmunity in neuropsychiatric diseases
(Applicant
Prüß, Harald
)
Visualizing BDNF cell-to-cell transfer and its effects on synapse and circuit function
(Applicant
Dean, Camin
)
Heisenberg Grants
Current projects
Molecular Mechanisms of Learning, Remembering and Forgetting
(Applicant
Dean, Camin
)
Collaborative Research Centres
Current projects
Development of molecular tools for manipulating and studying memory engrams
(Project Heads
Hegemann, Peter
;
Rosenmund, Christian
;
Rost, Benjamin
;
Schmitz, Dietmar
;
Vierock, Johannes
)
Nanoscale Dynamics and Regulation of Synapsin Condensates
(Project Head
Milovanovic, Dragomir
)
SFB 1286: Quantitative Synaptology
(Spokesperson
Rizzoli, Ph.D., Silvio-Olivier
)
SFB 1315: Mechanisms and disturbances in memory consolidation: From synapses to systems
(Spokesperson
Larkum, Matthew
)
Completed projects
Molekulare Analyse synaptischer Modulation: Proteininteraktionen metabotroper Rezeptoren
(Project Head
Kornau, Hans-Christian
)
SFB 958: Scaffolding of Membranes: Molecular Mechanisms and Cellular Functions
(Spokespersons
Haucke, Ph.D., Volker
;
Sigrist, Stephan J.
)
Synaptic Mechanisms underlying Phelan McDermid and Asperger's Syndrome
(Project Head
Garner, Craig C.
)
Synaptic scaffold proteins regulate presynaptic proteostasis
(Project Heads
Garner, Craig C.
;
Schmitz, Dietmar
)
The role of synaptotagmins in olfactory processing
(Project Head
Dean, Camin
)
Research Fellowships
Completed projects
Die Rolle von RIM 1 alpha und seinen Isoformen bei der Ausbildung und Funktion der präsynaptischen aktiven Zone
(Applicant
Bruederle, Cathrin
)
Mechanismen der Endocytose von synaptischen Vesikeln
(Applicant
Ackermann, Frauke
)
Mechanisms regulating the assembly, dynamics and stability of mammalian presynaptic active zones
(Applicant
Maas, Ph.D., Christoph
)
Signalspezifische Dynamik postssynaptischer Adapterproteine
(Applicant
Specht, Christian
)
Transsynaptic signaling influenced trough the dynamics of ProSAP/Shank proteins at excitatory synapses
(Applicant
Grabrucker, Andreas
)
Priority Programmes
Completed projects
Delineating and testing a microcircuit model of parahippocampal phase precession
(Applicants
Brecht, Michael
;
Kempter, Richard
;
Schmitz, Dietmar
)
Development and Application of New Optogenetic Tools Targeted to Intracellular Compartments
(Applicants
Hegemann, Peter
;
Rost, Benjamin
)
Engineering of Chrimson for Subcellular Optogenetic application
(Applicants
Elstner, Marcus
;
Hegemann, Peter
;
Rost, Benjamin
)
Research Units
Current projects
Developmental and synaptic defects caused by transplacental transmission of NMDA receptor antibodies
(Applicants
Kaindl, Angela
;
Kirmse, Knut
;
Prüß, Harald
)
FOR 3004: Synaptic pathology in autoimmune encephalitis – SYNABS
(Spokesperson
Geis, Christian
)
FOR 5228: Membrane trafficking processes underlying presynaptic proteostasis
(Spokesperson
Kreutz, Michael R.
)
Maintaining presynaptic function in dopaminergic synapses
(Applicants
Gundelfinger, Eckart D.
;
Rosenmund, Christian
)
Molecular mechanisms and in-vivo functional effects of antibodies in GABAB receptor autoimmune encephalitis
(Applicants
Geis, Christian
;
Kornau, Hans-Christian
;
Schmidt-Hieber, Christoph
)
Origin and Diversity of Pathogenic Human Monoclonal Antibodies and T cells in Tumor-associated Autoimmune Neurological Disorders
(Applicants
Prüß, Harald
;
Wahl, Ilka Maria
)
Completed projects
Origin and diversity of pathogenic human monoclonal antibodies to the NMDA receptor
(Applicants
Prüß, Harald
;
Wardemann, Hedda
)
Clinical Research Units
Current projects
Antibody target identification and novel diagnostics
(Applicants
Prüß, Harald
;
Wanker, Erich E.
)
Disease models and novel diagnostic imaging markers
(Applicants
Makowski, Marcus R.
;
Prüß, Harald
)
Establishing a Core Unit for Research and Treatment for patients with antibody-mediated neurological diseases
(Applicants
Prüß, Harald
;
Radbruch, Helena
;
Ripke, Stephan
)
KFO 5023: BECAUSE-Y Berlin Center for Diagnosing, Understanding and Treating Antibody(Y)-mediated Neurological Diseases
(Spokesperson
Endres, Matthias
)
CRC/Transregios
Current projects
Rewiring of GABAergic inhibitory cells recruited during spatial encoding
(Project Heads
Haberl, Matthias
;
Viana da Silva, Ph.D., Silvia
)
Clusters of Excellence (ExStra)
Current projects
EXC 2049: NeuroCure
(Spokespersons
Dirnagl, Ulrich
;
Schmitz, Dietmar
)
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