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Universitätsklinikum Münster
Klinik für Neurologie
mit Institut für Translationale Neurologie

Address Albert-Schweitzer-Campus 1
48149 Münster
Deutschland

GERiT This institution in GERiT

48149 Münster

Projects

Priority Programmes
- Completed projects
  - Charakterisierung residenter endoneuronaler Makrophagen in vivo im Vergleich mit Mikroglia und perivaskulären Zellen des Gehirns
    (Applicant Kiefer, Reinhard )
Research Grants
- Current projects
  - AntibodyOMICs in CASPR2 Encephalitis
    (Applicant Lünemann, Jan )
  - Autophagy in Microglia-mediated De- and Re-myelination
    (Applicant Lünemann, Jan )
  - Clinician Scientist CareerS Münster
    (Applicant Schäfers, Michael )
  - Next-generation immunological analysis of a cohort of monozygotic twins discordant for Multiple Sclerosis diagnosis.
    (Applicants Klotz, Luisa ; Schwab, Ph.D., Nicholas )
  - Origin, fate, and function of meningeal mature and progenitor B cells.
    (Applicant Meyer zu Hörste, Gerd )
- Completed projects
Heisenberg Grants
- Current projects
  - Understanding lymphocytes in nervous system border-associated compartments
    (Applicant Meyer zu Hörste, Gerd )
Research Fellowships
- Completed projects
Clinical Research Units
- Current projects
  - Immune System variables in healthy subjects and during systemic inflammation
    (Applicants Klotz, Luisa ; Rossaint, Jan ; Roth, Johannes )
  - KFO 342: Organ Dysfuncion During Systemic Inflammation
    (Spokesperson Zarbock, Alexander )
- Completed projects
  - Local control of inflammation neuronal damage by Peroxisome-profilator-activated receptory (PPARy) in EAE
    (Applicant Klotz, Luisa )
Collaborative Research Centres
- Completed projects
  - Mechanisms and consequences of immune-cell interactions with endothelial cells and pericytes at the blood-brain-barrier
    (Project Heads Klotz, Luisa ; Wiendl, Heinz )
  - Mechanisms of nuclear receptor-mediated control of TH17 cell differentiation
    (Project Head Klotz, Luisa )
CRC/Transregios
- Current projects
  - Dissecting the contribution of immune cell activation dependent neuronal connectivity changes to disease trajectories in depression
    (Project Heads Forstner, Andreas J. ; Klotz, Luisa ; Ziller, Michael J. )
  - Neutrophil modulation during cerebral ischemia by the nuclear receptor NR4A1
    (Project Heads Klotz, Luisa ; Minnerup, Jens )
- Completed projects
  - Analysis and therapeutic modifications of innate immune regulatory networks in controlling T-cell activation in MS
    (Project Heads Groß, Catharina C. ; Wiendl, Heinz )
  - Clinical translational Unit
    (Project Heads Fleischer, Vinzenz ; Gold, Ralf ; Hemmer, Bernhard ; Hohlfeld, Reinhard ; Klotz, Luisa ; Kuhlmann, Tanja ; Kümpfel, Tania ; Lehmann-Horn, Klaus ; Lüssi, Felix ; Meyer zu Hörste, Gerd ; Wiendl, Heinz ; Zipp, Frauke )
  - Immune regulation at the CNS barriers and in the CNS: role of immune cell trafficking
    (Project Heads Schwab, Ph.D., Nicholas ; Zarbock, Alexander )
  - Impact of diet and intestinal microbiota on the gut-CNS-axis – implications for CNS autoimmunity
    (Project Heads Klotz, Luisa ; Schuppan, Detlef )
  - MOG Antibody-Induced CNS Demyelination: from Specificity to Function
    (Project Heads Lünemann, Jan ; Meinl, Edgar )
  - Molecular mechanisms and sites of action of the gelatinases in autoimmune CNS inflammation: do MMP-2/-9 contribute to meningeal inflammation and secondary cortical damage?
    (Project Heads Meyer zu Hörste, Gerd ; Schäfers, Michael ; Sorokin, Lydia )
  - Temporal lobe epilepsy and advenced white matter fractional anisotropy analysis
    (Project Heads Deppe, Michael ; Elger, Christian E. ; Weber, Bernd )
  - The role of the kallikrein-kinin system to functional and structural impairment of network activity in multiple sclerosis
    (Project Heads Budde, Thomas ; Göbel, Kerstin ; Meuth, Sven G. ; Pape, Hans-Christian )
Research Units
- Current projects
  - Chronic inflammasome activation in post-stroke recovery
    (Applicants Hornung, Veit ; Liesz, Arthur ; Schmidt-Pogoda, Antje )
  - FOR 2879: ImmunoStroke: From immune cells to stroke recovery
    (Spokesperson Liesz, Arthur )
  - ImmunoStroke: From Immune Cells to Stroke Recovery Linking functional immune profiles and ischemic lesion characteristics in human stroke
    (Applicants Klotz, Luisa ; Thomalla, Götz ; Tolosa, Eva ; Wiendl, Heinz )
  - Meningeal immune cell priming for stroke recovery
    (Applicants Benakis, Corinne ; Meyer zu Hörste, Gerd ; Minnerup, Jens )
Research Training Groups
- Current projects
  - GRK 2515: Chemical Biology of Ion Channels (Chembion)
    (Spokesperson Wünsch, Bernhard )
NFDI technical and methodological consortia
- Current projects
  - National Research Data Infrastructure for Immunology
    (Spokesperson Busse, Christian )

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