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Universität zu Lübeck
Sektion Medizin
Lübecker Institut für Experimentelle Dermatologie

Address Ratzeburger Allee 160
23562 Lübeck
Deutschland

GERiT This institution in GERiT

23562 Lübeck

Projects

Research Grants
- Current projects
- Completed projects
Clinical Research Units
- Completed projects
  - Biostatistics and Systems Medicine Core Unit (Z2-Project)
    (Applicants Busch, Hauke ; Erdmann, Jeanette ; Koenig, Inke Regina ; Sadik, Christian David )
  - Central Clinical Infrastructure (Z1-Project)
    (Applicants van Beek, Nina ; Sadik, Christian David ; Schmidt, Enno ; Zillikens, Detlef )
  - Cutaneous complement C3 as key driver of pemphigoid disease pathogenesis
    (Applicants Ludwig, Ralf Joachim ; Verschoor, Ph.D., Admar )
  - Functional characterization and directed modulation of the skin microbiome in pemphigoid diseases
    (Applicants Baines, John F. ; Schmidt, Enno )
  - KFO 303: Pemphigoid Diseases - Molecular Pathways and their Therapeutic Potential
    (Spokesperson Zillikens, Detlef )
  - “Mitochondrial” Regulation of Pemphigoid Diseases
    (Applicants Hirose, Misa ; Ibrahim, Saleh M. )
  - Therapeutic potential of sialylated Pemphigoid Disease autoantibodies
    (Applicants Ehlers, Marc ; Hirose, Misa )
  - The role of C5aR2 in the pathogenesis of pemphigoid diseases
    (Applicants Karsten, Christian ; Schmidt, Enno )
  - The Role of Lymphocyte-derived Factors in the Effector Phase of Pemphigoid Diseases
    (Applicants Bieber, Katja ; Manz, Rudolf )
WBP Return Grant
- Completed projects
  - Rückkehrstipendium
    (Applicant Stefan, Katja )
Clinical Trials
- Completed projects
  - Efficacy and safety of adjuvant immunoadsorption in pemphigus
    (Applicants Eming, Rüdiger ; Schmidt, Enno )
Research Units
- Current projects
WBP Fellowship
- Completed projects
  - Design, synthesis, and biological assessment of ABC transporter agonists for the development of novel Alzheimer’s disease therapeutics
    (Applicant Stefan, Sven Marcel )
  - Establishment of new detection methods for the discovery and development of novel ABCA1 and ABCA7 modulators as Alzheimer’s disease (AD) therapeutics and diagnostics
    (Applicant Stefan, Katja )
Collaborative Research Centres
- Current projects
  - Autoantigen-specific T cells in pemphigoid diseases
    (Project Heads Scheffold, Alexander ; Schmidt, Enno )
  - Biostatistics, Systems Medicine, and Data Integration
    (Project Heads Fähnrich, Anke ; Szymczak, Silke )
  - Characterization and targeted modulation of the gut - skin axis in pemphigoid diseases
    (Project Heads Baines, John F. ; Ibrahim, Saleh M. )
  - Data management and bioinformatics
    (Project Head Busch, Hauke )
  - Information Infrastructure Project
    (Project Heads Busch, Hauke ; Franke, Andre ; Höppner, Ph.D., Marc )
  - Integrated Research Training Group
    (Project Heads Hundt, Jennifer ; Krämer, Ulrike M. ; Stammberger, Birgit )
  - Kinase cascades in neutrophils as therapeutic target in pemphigoid diseases
    (Project Heads Bieber, Katja ; Lux, Anja )
  - Multi-omics analysis of sex variability
    (Project Head Busch, Hauke )
  - Preclinical model systems of pemphigoid diseases
    (Project Heads Ludwig, Ralf Joachim ; Murthy, Sripriya )
  - Selective B cell depletion in pemphigoid diseases by bispecific antibodies
    (Project Heads Ludwig, Ralf Joachim ; Peipp, Matthias )
  - Site-specific inhibition of C5/C5a in pemphigoid diseases
    (Project Heads Ludwig, Ralf Joachim ; Peipp, Matthias )
  - Skin-infiltrating T and B cells in the pathogenesis of pemphigoid diseases
    (Project Heads Hutloff, Andreas ; Ibrahim, Saleh M. )
  - Targeting mitochondrial metabolism in pemphigoid diseases
    (Project Heads Hirose, Misa ; Väth, Ph.D., Martin )
- Completed projects
  - Systems biology, pathology and proteomics
    (Project Heads Busch, Hauke ; Börries, Melanie ; Laßmann, Silke ; Schilling, Oliver )
Priority Programmes
- Completed projects
  - Mixed Models in Cell Communication and Cancer
    (Applicants Busch, Hauke ; Börries, Melanie ; Theis, Fabian )
Research Training Groups
- Current projects
  - GRK 2633: Defining and Targeting Autoimmune Pre-Disease
    (Spokesperson Ludwig, Ralf Joachim )
- Completed projects
  - GRK 1727: Modulation of Autoimmunity
    (Spokesperson Zillikens, Detlef )
  - GRK 1743: Genes, Environment and Inflammation
    (Spokesperson Franke, Andre )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 2167: Precision Medicine in Chronic Inflammation (PMI)
    (Spokespersons Niemann, Stefan ; Riemekasten, Gabriela ; Schreiber, Stefan )

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