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Institution
Universitätsklinikum Jena
Zentrum für Molekulare Biomedizin
Institut für Molekulare Zellbiologie
Address
Hans-Knöll-Straße 2
07745 Jena
Deutschland
GERiT
This institution in GERiT
07745 Jena
Projects
Research Grants
Current projects
In vivo role of FLT3-CD45 signalling for bone remodelling
(Applicants
Hofbauer, Lorenz C.
;
Müller, Jörg P.
;
Rauner, Martina
)
Organ Dysfunction in Old Age: Perspectives for Young Clinician Scientists (OrganAge)
(Applicant
Witte, Otto Wilhelm
)
Role of SIRT7 in FLT3 ITD driven cell differentiation and transformation
(Applicant
Müller, Jörg P.
)
Completed projects
Characterisation of the delta pH-dependent protein translocation in Bacillus subtilis
(Applicant
Müller, Jörg P.
)
Characterization of a novel export specific chaperone of Bacillus subtilis
(Applicant
Müller, Jörg P.
)
Compartmentalized signalling of Ras in cancer cells
(Applicants
Böhmer, Frank-Dietmar
;
Rubio, Ignacio
)
Die Beeinflussung der endothelialen Stickstoffmonoxid(NO)-Synthese durch Hypochlorit (HOCl)-modifiziertes Lipoprotein niedriger Dichte (LDL)
(Applicant
Heller, Regine
)
Die Rolle von PDGF und PDGF-Rezeptoren für die Fibrosierung des Myokards im Modell der Coxsackievirus B3-induzierten Myokarditis
(Applicant
Böhmer, Frank-Dietmar
)
Oxidation-dependent degradation as a novel principle for regulation of protein-tyrosine phosphatases - role of PTP DEP-1 oxidation for transformation in AML
(Applicant
Böhmer, Frank-Dietmar
)
Oxidation of protein-tyrosine phosphatases in oncogenic cell transformation
(Applicant
Böhmer, Frank-Dietmar
)
Receptor protein-tyrosine phosphatases controlling activity of the oncoprotein FLT3 ITD
(Applicant
Müller, Jörg P.
)
Regulation and function of AMPK in endothelial cells
(Applicant
Heller, Regine
)
Regulation der Migration und Invasivität von Meningeomzellen durch die Protein-Tyrosinphosphatase DEP-1/PTPRJ
(Applicant
Böhmer, Frank-Dietmar
)
Selectivity and redundancy of protein-tyrosine phosphatases in the regulation of receptor tyrosine kinase signaling
(Applicant
Böhmer, Frank-Dietmar
)
Research Fellowships
Completed projects
Development of a fluorezence based testsystem to investigate the mechanism of activation of G protein-coupled receptors
(Applicant
Hoffmann, Carsten
)
CRC/Transregios
Completed projects
The interplay of receptor dynamics and ligand residence time upon ligand efficacy at adenosine receptors
(Project Head
Hoffmann, Carsten
)
Collaborative Research Centres
Current projects
Delivery platforms for antiviral and anti-inflammatory agents targeting infections of respiratory viruses with pandemic potential
(Project Heads
Ehrhardt, Christina
;
Hoffmann, Carsten
;
Löffler, Bettina
;
Schubert, Stephanie
)
Completed projects
Aktivierung, Desensibilisierung und Internalisierung G-Protein-gekoppelter Rezeptoren
(Project Heads
Hoffmann, Carsten
;
Lohse, Martin J.
)
Function and regulation of the tumour suppressor DEP-1
(Project Heads
Böhmer, Frank-Dietmar
;
Reißmann, Siegmund
)
Research Training Groups
Current projects
GRK 2155: ProMoAge - Protein Modification: A Key Mechanism for Ageing
(Spokesperson
Simm, Andreas
)
Completed projects
GRK 768: Biomolecular Switches ? Coding of Proteins via Conformational Changes and Posttranslational Modifications
(Spokesperson
Heinemann, Stefan H.
)
GRK 1715: Molecular Signatures of Adaptive Stress Responses
(Spokespersons
Heinzel, Thorsten
;
Wetzker, Reinhard
)
Additional Information
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