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Goethe-Universität Frankfurt am Main
Fachbereich Biochemie, Chemie und Pharmazie
Institut für Biochemie

Address Max-von-Laue-Straße 9
60438 Frankfurt am Main
Deutschland

GERiT This institution in GERiT

60438 Frankfurt am Main

Projects

Research Grants
- Current projects
  - Dissecting pre-tRNA splicing across scales: from molecules to cells
    (Applicant Trowitzsch, Simon )
  - Supramolecular organization of the antigen processing machinery in the ER membrane
    (Applicant Tampé, Robert )
  - Transmembrane signaling by in-situ receptor confinement
    (Applicant Tampé, Robert )
- Completed projects
Research Units
- Completed projects
Priority Programmes
- Completed projects
  - Cellular Logistics - Traceless protein modification by small high-affinity tags in living cells
    (Applicant Tampé, Robert )
  - Molecular basis for the control of K(+) uptake via KtrAB and KimA by cyclic di-AMP
    (Applicants Hänelt, Inga ; Vonck, Janet )
Reinhart Koselleck Projects
- Current projects
  - Deciphering MHC I chaperone complexes
    (Applicant Tampé, Robert )
Heisenberg Grants
- Current projects
  - Potassium transporters and channels in bacterial survival
    (Applicant Hänelt, Inga )
Collaborative Research Centres
- Current projects
  - Central Tasks of the Collaborative Research Center
    (Project Head Tampé, Robert )
  - Integrated Research Training Group
    (Project Head Hänelt, Inga )
  - Molecular basis of lipid transport across the periplasm
    (Project Head Pos, Klaas Martinus )
  - Protein assemblies and machineries in antigen processing and ER quality control
    (Project Head Tampé, Robert )
  - Regulation of potassium channel YugO in bacterial electrical signaling
    (Project Head Hänelt, Inga )
  - SFB 1507: Protein Assemblies and Machineries in Cell Membranes
    (Spokesperson Tampé, Robert )
  - Single-particle cryo-EM infrastructure
    (Project Heads Beck, Martin ; Tampé, Robert )
- Completed projects
  - Central Tasks of the Collaborative Research Center
    (Project Head Tampé, Robert )
  - Central tasks of the Collaborative Research Centre
    (Project Head Ludwig, Bernd )
  - Control of mRNA translation and ribosome recycling by ABCE1
    (Project Head Tampé, Robert )
  - Electron transport and proton translocation in bacterial respiratory chains
    (Project Head Ludwig, Bernd )
  - Functional modulation of the K+ transporter KtrAB in vivo and in vitro
    (Project Head Hänelt, Inga )
  - Function and mechanism of the lysosomal polypeptide transporter ABCB9
    (Project Head Abele, Rupert )
  - Function of the Transport Complex TAP
    (Project Heads Abele, Rupert ; Tampé, Robert )
  - Integrated Research Training Group
    (Project Head Pos, Klaas Martinus )
  - Kern-Cytoplasma-Transport
    (Project Head Fasold, Hugo )
  - Molecular Cross Talk at the Endothelial Membrane
    (Project Head Müller-Esterl, Werner )
  - Molekulare Mechanismen der Aktivitätsregulation von NO-Synthasen
    (Project Heads Müller-Esterl, Werner ; Oess, Stefanie )
  - SFB 472: Molecular Bioenergetics
    (Spokesperson Ludwig, Bernd )
  - SFB 628: Functional Membrane Proteomics - From Transport Machineries to Dynamic Assemblies and Networks
    (Spokesperson Tampé, Robert )
  - SFB 807: Transport and Communication across Biological Membrans
    (Spokesperson Tampé, Robert )
  - Structure and Function of the Mitochondrial Transport Complex Mdl1p from S. cerevisiae
    (Project Head Tampé, Robert )
  - Struktur-Funktions-Beziehung von dreiteiligen Arzneimittel-auswärtspumpenden RND-Komplexen s
    (Project Head Pos, Klaas Martinus )
  - Struktur und Funktion des ABC-Transportkomplexes TAP
    (Project Head Tampé, Robert )
  - Translocation mechanism of ABC exporters and the peptide-loading complex
    (Project Head Tampé, Robert )
  - Viral and Instrinsic Modulators
    (Project Head Tampé, Robert )
  - Virale Effektoren der Antigenprozessierung
    (Project Head Tampé, Robert )
  - Viral Inhibitors of the Antigen Processing Machinery
    (Project Head Tampé, Robert )
  - Zentrale Aufgaben
    (Project Head Tampé, Robert )
Research Fellowships
- Completed projects
  - Exploring the structural and mechanistic basis of H+, Na+, and K+ coupling in secondary active glutamate transporters
    (Applicant Hänelt, Inga )
Major Research Instrumentation
- Completed projects
  - Cryo-Transmission Electron Microscope 200 kV
  - Multiphotonen Konfokales Laserraster Fluoreszenzmikroskop
WBP Fellowship
- Completed projects
  - Unravelling lung adenocarcinoma paralog dependencies using in vivo combinatorial CRISPR screens
    (Applicant Elwakeel, Ph.D., Eiman )
Emmy Noether Independent Junior Research Groups
- Completed projects
  - Determinants of ion channel versus transporter mechanism in the K(+) transporter superfamily
    (Applicant Hänelt, Inga )
Research Training Groups
- Completed projects
  - GRK 541: Protein Function at the Atomic Level
    (Spokesperson Buckel, Wolfgang )
  - GRK 1986: Complex Scenarios of Light-Control
    (Spokesperson Heckel, Alexander )
Clusters of Excellence
- Completed projects
  - EXC 115: Macromolecular Complexes
    (Spokespersons Dötsch, Volker ; Schwalbe, Harald )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 3094: SCALE – SubCellular Architecture of LifE
    (Spokespersons Beck, Martin ; Hänelt, Inga ; Müller-McNicoll, Michaela )

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