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Institution
Universitätsklinikum Aachen, AöR
Medizinische Fakultät
Institut für Molekulare Pharmakologie
Address
Wendlingweg 2
52074 Aachen
Deutschland
GERiT
This institution in GERiT
52074 Aachen
Projects
Research Grants
Current projects
Regulation and Function of the Rhomboid Pseudoproteases iRhom1 and iRhom2 in Lung Inflammation
(Applicant
Ludwig, Andreas
)
Completed projects
Cell specific role of proteolytic shedding by the metalloproteinases ADAM10 and ADAM17 in chronic lung infammation
(Applicant
Ludwig, Andreas
)
Die Bedeutung von löslichen und transmembranen Varianten der CX3CL1 und CXCL16 bei vaskulären Entzündungsreaktionen
(Applicant
Ludwig, Andreas
)
Elektrophysiologische Struktur- und Funktionsanalyse von P2X-Purinozeptorkanälen
(Applicant
Schmalzing, Günther
)
Mechanism of cytolytic pore formation by the P2X7-receptor
(Applicant
Schmalzing, Günther
)
Micro fluidic system for characterization of endothelial permeability and transendothelial leucocyte migration
(Applicants
Ludwig, Andreas
;
Schnakenberg, Uwe
)
Molecular Dynamics Guided Analysis of Ligand Activation, Ion Permeation and Subtype-specific Ligand Interactions in P2X Receptors
(Applicant
Hausmann, Ralf
)
Regulation by ubiquitination of the inhibitory glycin receptor
(Applicant
Schmalzing, Günther
)
Regulation of the ion channel activities of the P2X7 receptor via its N and C terminal endodomains
(Applicants
Markwardt, Fritz
;
Schmalzing, Günther
)
Shedding proinflammatorischer Mediatoren durch die Metalloproteinasen ADAM10 und ADAM17 bei der entzündlichen Leukozytenrekrutierung
(Applicants
Ludwig, Andreas
;
Weber, Christian
)
Structure function relationships of P2X-receptor channels
(Applicant
Schmalzing, Günther
)
Traditional Chinese Herbs as Probes of P2X Receptors and other Ion Channels in the Pain Pathway
(Applicant
Schmalzing, Günther
)
Research Units
Completed projects
Characterization of affinity-tagged fluorescent P2X and P2Y receptors in BAC transgenic mice in health and disease
(Applicants
Franke, Heike
;
Schmalzing, Günther
)
Die Bedeutung von löslichen und transmembranen Varianten der Chemokine CX3CL1 und CXCL16 bei vaskulären Entzündungsreaktionen
(Applicant
Ludwig, Andreas
)
FOR 748: Neuronal and Glial P2 Receptors; Molecular Basis and Functional Significance
(Spokesperson
Schöneberg, Torsten
)
Struktur- und Funktionsanalyse von P2X-Rezeptorkanälen
(Applicant
Schmalzing, Günther
)
Z-Project (coordination and central funds)
(Applicant
Schöneberg, Torsten
)
Collaborative Research Centres
Completed projects
Mechanismus der P2X7-Rezeptor-vermittelten Zytokinfreisetzung
(Project Head
Schmalzing, Günther
)
Rolle kleiner GTP-bindender Proteine der Rho/Rac-Familie bei der Endo- und Exocytose
(Project Head
Schmalzing, Günther
)
Shedding of proinflammatory mediators by the metalloproteinases ADAM10 and ADAM17 during inflammatory leukocyte recruitment
(Project Heads
Ludwig, Andreas
;
Weber, Christian
)
Research Fellowships
Completed projects
Cell biology of signalling: how members of the rhomboid-like superfamily regulate multiple pathways
(Applicant
Düsterhöft, Stefan
)
Major Research Instrumentation
Completed projects
Real time imaging system for cell and tissue cultures
Priority Programmes
Current projects
EndOxy in Flame – Influence of a Biohybrid Lung on Inflammatory Pathways and Immune System-Endothelial Cell-Interaction
(Applicants
Jockenhövel, Stefan
;
Tenbrock, Klaus
)
Research Training Groups
Current projects
GRK 2415: Mechanobiology in Epithelial 3D Tissue Constructs
(Spokesperson
Leube, Rudolf E.
)
International Research Training Groups
Completed projects
GRK 1508: Arterial Remodelling
(Spokesperson
Bernhagen, Jürgen
)
Additional Information
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