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Institution
Universitätsklinikum Aachen, AöR
Medizinische Fakultät
Institut für Molekulare Pharmakologie
Address
Wendlingweg 2
52074 Aachen
Deutschland
GERiT
This institution in GERiT
52074 Aachen
Projects
Research Grants
Current projects
Interplay of the iRhom2/ADAM17 axis and Piezo1 in lung responses to inflammation and mechanical stress
(Applicant
Ludwig, Andreas
)
Completed projects
Cell specific role of proteolytic shedding by the metalloproteinases ADAM10 and ADAM17 in chronic lung infammation
(Applicant
Ludwig, Andreas
)
Die Bedeutung von löslichen und transmembranen Varianten der CX3CL1 und CXCL16 bei vaskulären Entzündungsreaktionen
(Applicant
Ludwig, Andreas
)
Elektrophysiologische Struktur- und Funktionsanalyse von P2X-Purinozeptorkanälen
(Applicant
Schmalzing, Günther
)
Mechanism of cytolytic pore formation by the P2X7-receptor
(Applicant
Schmalzing, Günther
)
Micro fluidic system for characterization of endothelial permeability and transendothelial leucocyte migration
(Applicants
Ludwig, Andreas
;
Schnakenberg, Uwe
)
Molecular Dynamics Guided Analysis of Ligand Activation, Ion Permeation and Subtype-specific Ligand Interactions in P2X Receptors
(Applicant
Hausmann, Ralf
)
Regulation by ubiquitination of the inhibitory glycin receptor
(Applicant
Schmalzing, Günther
)
Regulation of the ion channel activities of the P2X7 receptor via its N and C terminal endodomains
(Applicants
Markwardt, Fritz
;
Schmalzing, Günther
)
Shedding proinflammatorischer Mediatoren durch die Metalloproteinasen ADAM10 und ADAM17 bei der entzündlichen Leukozytenrekrutierung
(Applicants
Ludwig, Andreas
;
Weber, Christian
)
Structure function relationships of P2X-receptor channels
(Applicant
Schmalzing, Günther
)
Traditional Chinese Herbs as Probes of P2X Receptors and other Ion Channels in the Pain Pathway
(Applicant
Schmalzing, Günther
)
Research Units
Completed projects
Characterization of affinity-tagged fluorescent P2X and P2Y receptors in BAC transgenic mice in health and disease
(Applicants
Franke, Heike
;
Schmalzing, Günther
)
Die Bedeutung von löslichen und transmembranen Varianten der Chemokine CX3CL1 und CXCL16 bei vaskulären Entzündungsreaktionen
(Applicant
Ludwig, Andreas
)
FOR 748: Neuronal and Glial P2 Receptors; Molecular Basis and Functional Significance
(Spokesperson
Schöneberg, Torsten
)
Struktur- und Funktionsanalyse von P2X-Rezeptorkanälen
(Applicant
Schmalzing, Günther
)
Z-Project (coordination and central funds)
(Applicant
Schöneberg, Torsten
)
Collaborative Research Centres
Completed projects
Mechanismus der P2X7-Rezeptor-vermittelten Zytokinfreisetzung
(Project Head
Schmalzing, Günther
)
Rolle kleiner GTP-bindender Proteine der Rho/Rac-Familie bei der Endo- und Exocytose
(Project Head
Schmalzing, Günther
)
Shedding of proinflammatory mediators by the metalloproteinases ADAM10 and ADAM17 during inflammatory leukocyte recruitment
(Project Heads
Ludwig, Andreas
;
Weber, Christian
)
Research Fellowships
Completed projects
Cell biology of signalling: how members of the rhomboid-like superfamily regulate multiple pathways
(Applicant
Düsterhöft, Stefan
)
Major Research Instrumentation
Completed projects
Real time imaging system for cell and tissue cultures
Priority Programmes
Current projects
EndOxy in Flame – Influence of a Biohybrid Lung on Inflammatory Pathways and Immune System-Endothelial Cell-Interaction
(Applicants
Jockenhövel, Stefan
;
Tenbrock, Klaus
)
Research Training Groups
Current projects
GRK 2415: Mechanobiology in Epithelial 3D Tissue Constructs
(Spokesperson
Leube, Rudolf E.
)
International Research Training Groups
Completed projects
GRK 1508: Arterial Remodelling
(Spokesperson
Bernhagen, Jürgen
)
Additional Information
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