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Project Details

Institution

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Ludwig-Maximilians-Universität München (LMU)
Biomedizinisches Centrum
Munich Cluster for Systems Neurology (SyNergy)

Address Feodor-Lynen-Straße 17
81377 München
Deutschland

GERiT This institution in GERiT

81377 München

Projects

Research Grants
- Current projects
- Completed projects
Independent Junior Research Groups
- Completed projects
  - Molecular dissection of the human autophagy signaling pathway
    (Applicant Behrends, Ph.D., Christian )
Research Units
- Completed projects
  - FOR 2290: Understanding Intramembrane Proteolysis
    (Spokesperson Langosch, Dieter )
  - Functional role of transmembrane domain interactions and intramembrane cleavage of microglial innate immunity receptors
    (Applicant Haass, Christian )
Reinhart Koselleck Projects
- Completed projects
  - TREM2 dependent microglial function and dysfunction: A target for therapeutic modulation of Alzheimer's disease and Frontotemporal Dementia
    (Applicant Haass, Christian )
Heisenberg Grants
- Current projects
  - Unraveling molecular mechanisms of the preferential degeneration of midbrain neurons in neurodegenerative diseases
    (Applicant Burbulla, Lena )
Priority Programmes
- Completed projects
  - Molecular Mechanisms of Presenilin Function
    (Applicant Haass, Christian )
  - SPP 1085: Cellular Mechanisms of Alzheimer's Disease
    (Spokespersons Haass, Christian ; Multhaup, Gerhard )
  - The cellular basis of APP processing: trafficking and assembly of gamma-secretases and its substrates
    (Applicant Haass, Christian )
Collaborative Research Centres
- Current projects
  - Molecular analysis of physiological and BPAN-related WIPI4 functions
    (Project Heads Behrends, Ph.D., Christian ; Proikas-Cezanne, Tassula )
  - Quantitative proteomics and integrated systems biology
    (Project Heads Behrends, Ph.D., Christian ; Beli, Petra ; Bhaskara, Ph.D., Ramachandra M. ; Dikic, Ivan ; Hummer, Gerhard ; Münch, Christian )
- Completed projects
  - Administration, Travel, Meetings and Seminars of the Collaborative Research Centre
    (Project Head Haass, Christian )
  - Functional Analysis of ß-secretase (Bace) and Regulation of subcellular Trafficking
    (Project Head Haass, Christian )
  - Functional Characterization of y-Secretase
    (Project Heads Haass, Christian ; Steiner, Harald )
  - Post-transcriptional Regulation of ß-Secretase (Bace1) and a-Secretase (Adam10)
    (Project Heads Haass, Christian ; Lammich, Sven ; Willem, Michael )
  - Selective autophagy in proteostasis maintenance
    (Project Head Behrends, Ph.D., Christian )
  - SFB 596: Molecular Mechanisms of Neurodegeneration
    (Spokesperson Haass, Christian )
Major Research Instrumentation
- Completed projects
  - Hochleistungsmassenspektrometer mit nano-UHPLC Chromatographie-System
  - Liquid handling platform
Research Training Groups
- Completed projects
  - GRK 1373: Brain Signalling: From Neurons to Circuits
    (Spokesperson Konnerth, Arthur )
Clusters of Excellence
- Completed projects
  - EXC 1010: Munich Cluster for Systems Neurology (SyNergy)
    (Spokesperson Haass, Christian )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 2145: Munich Cluster for Systems Neurology (SyNergy)
    (Spokespersons Haass, Christian ; Misgeld, Thomas )

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