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Institution

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Universität Ulm
Fakultät für Naturwissenschaften
Institut für Proteinbiochemie

Address Helmholtzstraße 8/1
89081 Ulm
Deutschland

GERiT This institution in GERiT

89081 Ulm

Projects

Research Grants
- Current projects
  - Polymorphism of ATTR amyloid fibrils from human tissue
    (Applicant Fändrich, Marcus )
- Completed projects
  - Analysis of the effect of environmental factors on the structure of catalytic amyloid fibrils
    (Applicants Fändrich, Marcus ; Schmidt, Volker )
  - Biochemical and structural studies of amyloid enhancing factor
    (Applicant Fändrich, Marcus )
  - Mechanism and Structural Basis of SEVI-Mediated Enhancement of HIV Infection
    (Applicants Fändrich, Marcus ; Münch, Jan )
  - Role of C-terminal truncations of SAA protein for fibril formation and seeding in AA amyloidosis
    (Applicant Haupt, Christian )
  - Spezifität der Protein-Protein Wechselwirkung in Amyloidfibrillen und Proteinaggregaten
    (Applicant Fändrich, Marcus )
  - Structural analysis of SAA-amyloid fibrils by cryo-EM and NMR
    (Applicants Reif, Bernd ; Schmidt, Matthias )
  - Structural basis of biological active β-amyloid conformers
    (Applicants Fändrich, Marcus ; Jucker, Mathias )
  - Structure and propagation of beta-amyloid aggregates
    (Applicant Fändrich, Marcus )
Heisenberg Fellowships
- Completed projects
  - Biochemie
    (Applicant Fändrich, Marcus )
Research Units
- Completed projects
  - Coordination Funds
    (Applicant Fändrich, Marcus )
  - Cryo-EM structures of AL amyloid fibrils from human heart
    (Applicant Fändrich, Marcus )
  - FOR 2969: Mechanisms of antibody light chain misfolding in systemic AL amyloidosis
    (Spokesperson Fändrich, Marcus )
  - Variation of the AL protein primary structure in two clinical variants of AL amyloidosis
    (Applicants Haupt, Christian ; Hegenbart, Ute )
Major Research Instrumentation
- Completed projects
  - 200 kV Kryo-Transmissionselektronenmikroskop
  - Transmissionselektronenmikroskop
Collaborative Research Centres
- Current projects
  - Amyloid biology of bioinspired peptides - from basic research to preclinical development
    (Project Heads Fändrich, Marcus ; Münch, Jan ; Walther, Paul )
- Completed projects
  - Analysis of the structure and aggregation properties of natural and disease-related variants of the Alzheimer's Aß peptide
    (Project Head Fändrich, Marcus )

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