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Institution

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Rheinische Friedrich-Wilhelms-Universität Bonn
Pharmazeutisches Institut
Pharmazeutische Biochemie und Bioanalytik

Address An der Immenburg 4
53121 Bonn
Deutschland

GERiT This institution in GERiT

53121 Bonn

Projects

Research Grants
- Current projects
  - Biochemical basis of the interactions of heme with scavenger plasma proteins: analysis, quantification and approaches to intervention
    (Applicant Imhof, Diana )
- Completed projects
  - Modulation der katalytischen Aktivität von SHP-1 und SHP-2 durch alternative Arten der Phosphopeptidbindung
    (Applicant Imhof, Diana )
  - Screening-based design, synthesis and testing of potential Gα protein inhibitors as chemical probes for GPCR signaling
    (Applicant Imhof, Diana )
Priority Programmes
- Completed projects
  - How conformation matters: Ionic liquids as reaction media for oxidative folding and native chemical ligation of cysteine-containing peptides
    (Applicant Imhof, Diana )
  - Innovative Pharmaceutical Stabilization and Formulation Techniques for Protein Drugs and Their Influence on Sequence and Structure
    (Applicants Imhof, Diana ; Kühl, Toni ; Lamprecht, Alf ; Wagner, Karl G. )
Research Units
- Completed projects
  - Impact of heme and heme degradation products on peptides and proteins
    (Applicants Imhof, Diana ; Ohlenschläger, Oliver )
  - Synthesis and characterization of macrocyclic peptide inhibitors of the Galpha protein family
    (Applicant Imhof, Diana )
Major Research Instrumentation
- Completed projects
  - LC-ESI-MS/MS-System
  - Proteinsequenzer
Collaborative Research Centres
- Completed projects
  - Coordination of protoporphyrin IX-iron-complexes to hem-regulated proteins studied by EPR-spectroscopy and X-ray crystallography
    (Project Heads Hagelueken, Gregor ; Imhof, Diana ; Schiemann, Olav )

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