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Project Details

Institution

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Deutsches Krebsforschungszentrum (DKFZ)
FSP Funktionelle und strukturelle Genomforschung
Abteilung Chromatin-Netzwerke

Address Im Neuenheimer Feld 280
69120 Heidelberg
Deutschland

GERiT This institution in GERiT

69120 Heidelberg

Projects

Research Grants
- Completed projects
Priority Programmes
- Current projects
  - Functional organization of co-regulated RNA polymerase II nuclear subcompartments activated by TNFα or TGFβ
    (Applicant Rippe, Karsten )
  - Revealing the contribution of phase separation for establishing heterochromatin domains
    (Applicants Imhof, Axel ; Rippe, Karsten )
- Completed projects
  - Analysis of the in vivo chromatin conformation by high resolution fluorescence microscopy
    (Applicant Rippe, Karsten )
Research Units
- Current projects
  - FOR 2674: Aging-related epigenetic remodeling in acute myeloid leukemia
    (Spokesperson Lübbert, Ph.D., Michael )
- Completed projects
  - Dissecting AML transcriptome and chromatin networks by single cell sequencing to reveal cell heterogeneity and drug response mechanisms
    (Applicants Mallm, Jan-Philipp ; Rippe, Karsten )
Collaborative Research Centres
- Completed projects
  - Bioinformatics core - semantic knowledge fusion and non-standard optimization - Next Generation Sequencing core
    (Project Heads Kestler, Hans A. ; Rippe, Karsten )
  - Dissecting AML treatment response to FLT3 inhibitors by single-cell sequencin
    (Project Heads Döhner, Konstanze ; Rippe, Karsten )
CRC/Transregios
- Current projects
  - Experimental and computational single-cell analysis with high spatial resolution
    (Project Heads Herrmann, Carl ; Rippe, Karsten )
Research Training Groups
- Completed projects
  - GRK 886: Molecular imaging methods for the analysis of gene + protein expression
    (Spokesperson Gretz, Norbert )

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