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Institution
Martin-Luther-Universität Halle-Wittenberg
Institut für Biochemie und Biotechnologie
Abteilung Allgemeine Biochemie
Address
Kurt-Mothes-Straße 3a
06120 Halle
Deutschland
GERiT
This institution in GERiT
06120 Halle
Projects
Research Grants
Current projects
RNA-seq-based screening for active self-cleaving ribozymes and transcriptome-wide assessment of their regulatory functions
(Applicants
Fallmann, Ph.D., Jörg
;
Weinberg, Christina E.
)
Unravelling the biological roles of self-cleaving ribozymes in bacteria
(Applicant
Weinberg, Christina E.
)
Completed projects
Charakterisierung einer Poly(A)-spezifischen 3`-Exoribonuklease und ihrer Rolle bei der Deadenylierung von mRNA
(Applicant
Wahle, Elmar
)
Composition, structure and interactions of the Cleavage and Polyadenylation Specificity Factor (CPSF) involved in mammalian mRNA 3' end processing
(Applicant
Wahle, Elmar
)
Deadenylierende Enzyme aus Drosophila melanogaster und der Abbau der hsp70-mRNA
(Applicant
Wahle, Elmar
)
Die Rolle von Trinukleotidexpansionen im Gen für das Poly(A)-Bindungsprotein II (PABP 2) bei der Oculopharyngealen Muskeldystrophie (OPMD)
(Applicant
Wahle, Elmar
)
FLUOR - Fluorinated Surfactants for Membrane-Protein Research
(Applicants
Keller, Sandro
;
Meister, Annette
)
In vitro reconstitution of mammalian pre-mRNA 3' processing
(Applicant
Wahle, Elmar
)
Molecular aspects of mRNA regulation by piRNAs and RNA binding proteins in Drosophila
(Applicant
Wahle, Elmar
)
PAPD5 as an example for "dual-use" nucleotidyltransferases in human cells that can act as poly(A) as well as poly(U) polymerases
(Applicant
Rammelt, Christiane
)
Polyadenylierung von mRNA: Kontrolle der Poly(A)-Schwanzlänge
(Applicant
Wahle, Elmar
)
Research Units
Completed projects
3`-Processing of mRNA: Composition and dynamics of the processing complex and reconstitution of selected factors
(Applicant
Wahle, Elmar
)
Complex RNA-protein interactions in the maturation and functions of eukaryotic mRNA
(Applicant
Wahle, Elmar
)
FOR 426: Complex RNA-protein interactions in the maturation and function of eukaryotic mRNA
(Spokesperson
Wahle, Elmar
)
FOR 855: Cytoplasmic Regulation of Gene Expression
(Spokespersons
Fischer, Utz
;
Wahle, Elmar
)
Posttransscriptonal regulation of the nanos mRNA in Drosophila melanogaster
(Applicant
Wahle, Elmar
)
The role of the poly(A)-specific ribonuclease (PARN) in mRNA decay
(Applicant
Wahle, Elmar
)
Zentralprojekt
(Applicant
Fischer, Utz
)
Priority Programmes
Completed projects
Formation of the repressed nanos mRNP in the early Drosophila embryo
(Applicant
Wahle, Elmar
)
Research Fellowships
Completed projects
Quest for riboswitches in eukaryotes and identification of orphan riboswitch ligands
(Applicant
Weinberg, Christina E.
)
CRC/Transregios
Completed projects
Mechanisms of early amyloid formation and the confining influence of macromolecular crowding
(Project Head
Ott, Ph.D., Maria
)
Collaborative Research Centres
Completed projects
The asymmetric dimethylation of arginine side chains in the nuclear poly(A)binding protein (PABPN1)
(Project Head
Wahle, Elmar
)
Research Training Groups
Current projects
GRK 2467: Intrinsically Disordered Proteins – Molecular Principles, Cellular Functions, and Diseases
(Spokesperson
Sinz, Andrea
)
Completed projects
GRK 1026: Conformational Transitions in Macromolecular Interactions
(Spokesperson
Stubbs, Milton T.
)
GRK 1591: Posttranscriptional Control of Gene Expression: Mechanisms and Role in Pathogenesis
(Spokesperson
Hüttelmaier, Stefan
)
Additional Information
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