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Project Details

Institution

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Max-Planck-Institut für Biophysik
Abteilung für Membran-Dynamik

Address Max-von-Laue-Straße 3
60438 Frankfurt am Main
Deutschland

GERiT This institution in GERiT

60438 Frankfurt am Main

Projects

Research Units
- Completed projects
  - FOR 2036: New Insights into Bcl-2 Family Interactions: From Biophysics to Function
    (Spokesperson Brunner, Thomas )
  - Stoichiometry of homo- and hetero-complexes of Bcl-2 proteins at the single molecule level
    (Applicant Garcia Sáez, Ana Jesús )
Research Grants
- Completed projects
  - Mechanisms of MLKL in necroptosis: from intramolecular rearrangements to isoform regulation
    (Applicant Garcia Sáez, Ana Jesús )
  - Structural dynamics of membrane-bound BAX oligomers: intramolecular flexibility vs population heterogeneities
    (Applicants Bordignon, Enrica ; Garcia Sáez, Ana Jesús )
Priority Programmes
- Current projects
  - The wave of death: ferroptosis propagation from single cell death to tissue damage
    (Applicant Garcia Sáez, Ana Jesús )
Major Research Instrumentation
- Completed projects
  - 3D STED Super-resolution Confocal Microscope
  - Konfokales Mikroskop mit FCS-Modul
Collaborative Research Centres
- Current projects
- Completed projects
  - Effect of Bcl-2 proteins on mitochondrial structure, dynamics and function
    (Project Head Garcia Sáez, Ana Jesús )
CRC/Transregios
- Current projects
  - Death pores: decision-making at the execution step of regulated necrosis
    (Project Head Garcia Sáez, Ana Jesús )
  - Necroptosis in aortic aneurysm disease - significance of inflammation in MLKL dependent cell death
    (Project Heads Adam, Matti ; Garcia Sáez, Ana Jesús ; Pasparakis, Manolis )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 2180: Image-Guided and Functionally Instructed Tumor Therapies (iFIT)
    (Spokespersons Pichler, Bernd ; Rammensee, Hans-Georg ; Walz, Juliane ; Zender, Lars )

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