Project Details
Projekt
SFB 599: Sustainable Bioresorbable and Permanent Implants of Metallic and Ceramic Materials
Subject Area
Medicine
Materials Science and Engineering
Materials Science and Engineering
Term
from 2003 to 2014
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 5485789
The Collaborative Research Centres working programme is devided into two project fields, "R" and "D". These are the initials of German words, "R" for "resorbable" (= temporary) and "D" for "permanent" implants with 5 and 7 subprojects, respectively.
-- In Project Section R, resorbable implants will be developed. At the same time, the whole range of development will be covered by the variable coordination of the subproject fields. Together with other disciplines and in a continuous feedback, the material sciences create the original material, whose structuring, working and function is coordinated with regard to individual application. By means of simulation and calculation methods, an abstract image of the reality in models will be reached, the aim of which is to show the actual sequences and procedures through comparison, adjustment and approach so that resulting problems from implant materials and implants can be predicted and prevented in advance. In Project Section R, the reference to medicine in view of the living organism is also made, as here the applied materials and procedures with the themes of cell biology and biocompatibility will be examined concerning their influence on cells and tissue, e.g. by absorption, and will be further developed.
-- In Project Section D, permanent implants are the main interest. Besides the development of adapted basic material, the material behaving as inertly as possible during the application period, especially the surface, is given special attention. Thus the function and durability of each implant will be largely determined by its shape. In this project section with the development of material, shaping, working and coating, the required interface features will be especially determined, examined and finally created for application.
-- In Project Section R, resorbable implants will be developed. At the same time, the whole range of development will be covered by the variable coordination of the subproject fields. Together with other disciplines and in a continuous feedback, the material sciences create the original material, whose structuring, working and function is coordinated with regard to individual application. By means of simulation and calculation methods, an abstract image of the reality in models will be reached, the aim of which is to show the actual sequences and procedures through comparison, adjustment and approach so that resulting problems from implant materials and implants can be predicted and prevented in advance. In Project Section R, the reference to medicine in view of the living organism is also made, as here the applied materials and procedures with the themes of cell biology and biocompatibility will be examined concerning their influence on cells and tissue, e.g. by absorption, and will be further developed.
-- In Project Section D, permanent implants are the main interest. Besides the development of adapted basic material, the material behaving as inertly as possible during the application period, especially the surface, is given special attention. Thus the function and durability of each implant will be largely determined by its shape. In this project section with the development of material, shaping, working and coating, the required interface features will be especially determined, examined and finally created for application.
DFG Programme
Collaborative Research Centres
Completed projects
- D01 - Functionalized Middle Ear Prostheses (Project Heads Behrens, Peter ; Jacob, Hans-Georg ; Lenarz, Thomas ; Müller, Peter Paul ; Stieve, Martin )
- D02 - Development of electrode-arrays for optimised electrode-nerv-interaction (Project Heads Chichkov, Boris ; Lenarz, Thomas ; Menzel, Henning )
- D03 - Rapid Prototyping von artikulären metallischen Endoprotheasen mit angepasster Elastizität - Kurztitel: Implantat Prototyping (Project Heads Bunte, Jens ; Hurschler, Christof ; Ostendorf, Andreas ; Stukenborg-Colsman, Christina )
- D04 - Ceramic Implants (Project Heads Denkena, Berend ; Hurschler, Christof )
- D05 - Tribosystemoptimierung der Gleitpaarung künstlicher Gelenke - Kurztitel: Trivosystemoptimierung (Project Heads Nolte, Ingo ; Schmidt-jürgensen, Rune ; Windhagen, Henning ; Wirth, Carl Joachim )
- D06 - Numerical simulation on stress-compatible design of total prosthetic joint replacements and implants (Project Heads Behrens, Bernd-Arno ; Nolte, Ingo ; Stukenborg-Colsman, Christina )
- D07 - Implants surfaces (Project Heads Dempwolf, Wibke ; Gross, Gerhard ; Windhagen, Henning )
- D08 - Chemical functionalization of dental implant abutments for reduction of oral biofilm formation (Project Heads Abraham, Wolf-Rainer ; Menzel, Henning ; Stiesch, Meike )
- D09 - Production, processing and mechanical testing of biomimetic ceramics (Project Heads Behrens, Peter ; Denkena, Berend ; Menzel, Henning ; Ostermeier, Sven )
- D10 - Implants with alterable stiffness (Project Heads Barcikowski, Stephan ; Gösling, Thomas ; Herzog, Dirk ; Hurschler, Christof ; Meier, Oliver ; Müller, Christian ; Wesling, Volker )
- D12 - Dental ceramics and Composites (Project Heads Behrens, Peter ; Stiesch, Meike )
- D13 - Development, metal-forming and evaluation of patient-individual cetabular components (Project Heads Bouguecha, Anas ; Stukenborg-Colsman, Christina ; Wefstaedt, Patrick )
- DR01 - Mg-compounds on permanent implants (Project Heads Hauser, Hansjörg ; Möhwald, Kai ; Windhagen, Henning )
- MGK - Integrated Research Training Group (Project Heads Behrens, Peter ; Wriggers, Peter )
- R01 - Magnesium Degradation (Project Heads Bach, Friedrich-Wilhelm ; Bormann, Dirk ; Kietzmann, Manfred ; Lenarz, Thomas )
- R02 - Magnesium sponges as bioabsorbable implants (Project Heads Bormann, Dirk ; Hauser, Hansjörg ; Jacob, Hans-Georg ; Meyer-Lindenberg, Andrea ; Windhagen, Henning ; Wriggers, Peter )
- R03 - Zellbiologische Bewertung von mikrostrukturierten Kardiovaskulären Implantaten auf Eisenbasis - Kurztitel: Eisenresorption (Project Heads Hauser, Hansjörg ; Lubatschowski, Holger ; Peuster, Matthias )
- R04 - Functionally adjusted working of medical implants (Project Heads Denkena, Berend ; Meyer-Lindenberg, Andrea ; Thorey, Fritz )
- R06 - Degradable osteosynthesis systems (Project Heads Meyer-Lindenberg, Andrea ; Reifenrath, Janin ; Thorey, Fritz ; Windhagen, Henning ; Wriggers, Peter )
- R07 - Structures made of magnesium for the stabilization of cardiovascular tissue scaffolds in the high pressure system (Project Heads Hassel, Thomas ; Haverich, Axel ; Wriggers, Peter )
- R08 - Control of the degradation and mode of action of magnesium-based medical implants (Project Heads Glasmacher, Birgit ; Hauser, Hansjörg ; Kietzmann, Manfred )
- T01 - Development and production of microstructured electrode surfaces to reduce connective tissue growth on cochlear implants (Project Heads Chichkov, Boris ; Stöver, Timo )
- T02 - Nano-functionalized cochlear implants for optimized electrode nerve interaction (Project Heads Chichkov, Boris ; Lenarz, Thomas ; Paasche, Gerrit )
- T03 - Design, safe machining and performance of load bearing resorbable large fragment screws made of magnesium (Project Heads Denkena, Berend ; Windhagen, Henning )
- T04 - Innovative Grinding Tools for Concave Profile Grinding of Complex Shaped Bioceramics (Project Head Denkena, Berend )
- T05 - Entwicklung von Methoden zur Herstellung und automatisierten Bearbeitung schädigungstoleranter, gehipter Zr02-Keramiken für Dentalanwendungen (Project Head Köhler, Jens )
- Z01 - Verwaltung / Zentrale Aufgaben des Sonderforschungsbereichs (Project Head Lenarz, Thomas )
- Ö - Public relations in Collaborative Research Centers (Project Head Schilling, Tobias )
Applicant Institution
Medizinische Hochschule Hannover
Participating University
Hochschule Hannover
Fakultät IV - Wirtschaft und Informatik; Gottfried Wilhelm Leibniz Universität Hannover; Stiftung Tierärztliche Hochschule Hannover; Technische Universität Braunschweig
Fakultät IV - Wirtschaft und Informatik; Gottfried Wilhelm Leibniz Universität Hannover; Stiftung Tierärztliche Hochschule Hannover; Technische Universität Braunschweig
Participating Institution
Helmholtz-Zentrum für Infektionsforschung (HZI); Laser Zentrum Hannover e.V. (LZH)
Spokesperson
Professor Dr. Thomas Lenarz
