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Institution

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HI-STEM gGmbH
im Deutschen Krebsforschungszentrum DKFZ

Address Im Neuenheimerfeld 280
69120 Heidelberg
Deutschland

GERiT This institution in GERiT

69120 Heidelberg

Projects

Research Units
- Current projects
  - FOR 2033: The Hematopoietic Niches
    (Spokesperson Oostendorp, Robert A.J. )
  - FOR 2674: Aging-related epigenetic remodeling in acute myeloid leukemia
    (Spokesperson Lübbert, Ph.D., Michael )
- Completed projects
Research Grants
- Completed projects
  - Analysis of the metastatic niche in breast cancer progression: Defining the role of osteopontin in metastasis and therapy resistance
    (Applicant Oskarsson, Ph.D., Thordur )
Priority Programmes
- Current projects
  - Characterization and exploitation of novel ferroptosis regulators to target MYCN amplified cancers
    (Applicant Trumpp, Ph.D., Andreas )
  - Exploring selenocysteine metabolism as a targeted therapy approach in cancer
    (Applicant Alborzinia, Ph.D., Hamed )
WBP Position
- Current projects
  - Immune escape of DNMT3A R882 mutant hematopoietic stem and progenitor cells in clonal hematopoiesis
    (Applicant Stelmach, Patrick )
Collaborative Research Centres
- Completed projects
  - A novel level of regulation of normal and leukemic stem cell hierarchies by differential polyad-enylation of key transcripts
    (Project Head Trumpp, Ph.D., Andreas )
  - HSCs under acute and chronic inflammatory stress
    (Project Heads Essers, Marieke ; Milsom, Michael )
  - The effect of IFNa signaling on hematopoietic stem cells
    (Project Head Essers, Marieke )

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