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Institution
Constructor University Bremen
School of Science
Research Group Molecular Mechanisms of the Immune Response and Immuno-Biotechnology
Address
Campus Ring 1
28759 Bremen
Deutschland
GERiT
This institution in GERiT
28759 Bremen
Projects
Research Grants
Current projects
Deciphering the rules of genome binding specificity: de-novo design of intrinsically disordered regions directing transcription factor binding.
(Applicant
Springer, Sebastian
)
Decrypting MHC class I trafficking in cross-presentation
(Applicant
Springer, Sebastian
)
Mechanisms and consequences of functional divergence in transcription factor paralogs
(Applicant
Springer, Sebastian
)
The causes of MHC-I-opathies in cellular stress
(Applicant
Springer, Sebastian
)
Completed projects
Cell surface clusters of MHC class I molecules: origin, structure, and functions
(Applicant
Springer, Sebastian
)
Endocytic sorting of MHC class I molecules
(Applicant
Springer, Sebastian
)
Enhancement of peptide binding to MHC class I molecules by small compounds - a combined biochemical and computational investigation
(Applicants
Springer, Sebastian
;
Zacharias, Martin
)
Molecular cell biology of MHC class I retention by the gp40 protein of the murine cytomegalovirus
(Applicant
Springer, Sebastian
)
Small molecules to manipulate peptide binding to MHC class I molecules, an optimized method for the generation of MHC tetramers by peptide exchange
(Applicant
Springer, Sebastian
)
The intracellular quality control mechanism of major histocompatibility complex class I molecules studied by controlled peptide delivery to cells - a combined cell biological, biochemical, and biophysical investigation
(Applicant
Springer, Sebastian
)
The Regulated Intracellular Trafficking and Function of the Chaperones of the MHC Class I Peptide Loading Complex
(Applicant
Springer, Sebastian
)
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