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Professor Dr. Kay Grobe

Address Universitätsklinikum Münster
Institut für Physiologische Chemie und Pathobiochemie
Waldeyerstraße 15
48149 Münster

Projects

As Applicant
- Current projects
  - The role of direct heparan sulfate interactions and Ca2+ complexation in Hedgehog gradient formation in vivo (Research Grants)
- Completed projects
  - Differential roles of the N-acetylglucosamine N-deacetylase/N-sulfotransferase (NDST) isozymes 1-4 in the development of the mouse (Research Fellowships)
  - In vivo function of differentially processed Hedgehog morphogens (Research Grants)
  - Processed Sonic hedgehog - an active signaling protease? (Research Grants)
  - The role of the extracellular matrix constituent heparan sulfate in Hedgehog morphogen function (Heisenberg Professorships)
  - Biological roles of heparan sulfate in Hedgehog-dependent signaling and morphogenetic gradient formation (Heisenberg Grants)
As Participating Researcher
- Completed projects
  - GRK 1549: Molecular and Cellular Glyco-Sciences (MCGS). Understanding Structure/Function Relationships of Carbohydrate/Protein Interactions (International Research Training Groups)
As Project Head
- Current projects
  - Molecular parameters for the dynamic assembly of Hedgehog signaling platforms (Collaborative Research Centres)
- Completed projects
  - Roles of Heparan Sulfate in Sonic Hedgehog (Shh) Gradient Formation and Cardiac Development in the Mouse (Collaborative Research Centres)

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