Funktionen des zellulären Prion Proteins für die Entwicklung von Zell-Zell Kontakten und Axonwachstum

• Applicant: Professorin Dr. Claudia Stürmer
• Subject Area: Developmental Neurobiology
• Term: from 2009 to 2014
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 126074341

• Final Report Year: 2016

Final Report Abstract

No abstract available

Publications

• Regulation of cell spreading, focal adhesion formation and filopodia extension by the cellular prion protein. FEBS Letters, Vol. 583. 2009, Issue 2, pp. 389–393.
  Schrock Y., Solis G.P., Stuermer C.A.O.
  (See online at https://dx.doi.org/10.1016/j.febslet.2008.12.038)
• The cellular prion protein (PrPc) and reggies in cell adhesion. Dissertation, University of Konstanz, 2010.
  Schrock, Yvonne
  
• The reggie/flotillin connection to growth. Trends in Cell Biology, Vol. 20. 2010, Issue 1, pp. 6–13.
  Stuermer, C.A.O.
  (See online at https://dx.doi.org/10.1016/j.tcb.2009.10.003)
• PrP promotes growth cone development through reggie/flotillin-dependent N-cadherin trafficking. Journal of Neuroscience, Vol. 31. 2011, Issue 49, pp. 18013-18025.
  Bodrikov, V., Solis, G.P., Stuermer, C.A.O.
  (See online at https://dx.doi.org/10.1523/JNEUROSCI.4729-11.2011)
• Reggies/Flotillins regulate E-cadherin-mediated cell contact formation through EGFRs trafficking. Molecular Biology of the Cell, vol. 23. 2012, no. 10, pp. 1812-1825.
  Solis, G.P., Schrock, Y., Hülsbusch, N., Wiechers, M., Plattner, H., Stuermer, C.A.O.
  (See online at https://doi.org/10.1091/mbc.E11-12-1006)
• Conserved roles of the prion protein domains on subcellular localization and cell-cell adhesion. PLoS ONE, Vol. 8. 2013, Issue 7: e70327.
  Solis, G.P., Radon, Y., Sempou, A., Jechow, K., Stuermer, C.A.O., Málaga Trillo, E.
  (See online at https://doi.org/10.1371/journal.pone.0070327)
• Reggies/flotillins associate with the tubulo-vesicular recycling compartment and function in transferrin receptor and E-cadherin trafficking. Molecular Biology of the Cell, Vol. 24. 2013, no. 17, pp. 2689-2702.
  Solis, G. P., Hülsbusch, N., Radon, Y., Plattner, H., Stuermer, C. A. O.
  (See online at https://dx.doi.org/10.1091/mbc.E12-12-0854)
• Reggie-1/Flotillin-2 regulates integrin trafficking and focal adhesion turnover via Rab11a. European Journal of Cell Biology, Vol. 94. 2015, Issue 11, pp. 531–545.
  Hülsbusch, N., Solis G.P., Katanaev V.L., Stuermer C.A.O.
  (See online at https://doi.org/10.1016/j.ejcb.2015.07.003)
• The role of reggie/flotillin in signaling and membrane trafficking. Dissertation, University of Konstanz, 2015.
  Hülsbusch, Nikola