Funktionen des zellulären Prion Proteins für die Entwicklung von Zell-Zell Kontakten und Axonwachstum

• Applicant: Professorin Dr. Claudia Stürmer
• Subject Area: Developmental Neurobiology
• Term: from 2009 to 2014
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 126074341

• Final Report Year: 2016

Final Report Abstract

No abstract available

Publications

• Regulation of cell spreading, focal adhesion formation and filopodia extension by the cellular prion protein. FEBS Letters, Vol. 583. 2009, Issue 2, pp. 389–393.
  Schrock Y., Solis G.P., Stuermer C.A.O.
  
• The cellular prion protein (PrPc) and reggies in cell adhesion. Dissertation, University of Konstanz, 2010.
  Schrock, Yvonne
  
• The reggie/flotillin connection to growth. Trends in Cell Biology, Vol. 20. 2010, Issue 1, pp. 6–13.
  Stuermer, C.A.O.
  
• PrP promotes growth cone development through reggie/flotillin-dependent N-cadherin trafficking. Journal of Neuroscience, Vol. 31. 2011, Issue 49, pp. 18013-18025.
  Bodrikov, V., Solis, G.P., Stuermer, C.A.O.
  
• Reggies/Flotillins regulate E-cadherin-mediated cell contact formation through EGFRs trafficking. Molecular Biology of the Cell, vol. 23. 2012, no. 10, pp. 1812-1825.
  Solis, G.P., Schrock, Y., Hülsbusch, N., Wiechers, M., Plattner, H., Stuermer, C.A.O.
  
• Conserved roles of the prion protein domains on subcellular localization and cell-cell adhesion. PLoS ONE, Vol. 8. 2013, Issue 7: e70327.
  Solis, G.P., Radon, Y., Sempou, A., Jechow, K., Stuermer, C.A.O., Málaga Trillo, E.
  
• Reggies/flotillins associate with the tubulo-vesicular recycling compartment and function in transferrin receptor and E-cadherin trafficking. Molecular Biology of the Cell, Vol. 24. 2013, no. 17, pp. 2689-2702.
  Solis, G. P., Hülsbusch, N., Radon, Y., Plattner, H., Stuermer, C. A. O.
  
• Reggie-1/Flotillin-2 regulates integrin trafficking and focal adhesion turnover via Rab11a. European Journal of Cell Biology, Vol. 94. 2015, Issue 11, pp. 531–545.
  Hülsbusch, N., Solis G.P., Katanaev V.L., Stuermer C.A.O.
  
• The role of reggie/flotillin in signaling and membrane trafficking. Dissertation, University of Konstanz, 2015.
  Hülsbusch, Nikola