Dynamics of intermediate filament self-assembly (B07)

• Subject Area: Biophysics
• Term: from 2009 to 2019
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 28586557

Intermediate filaments in the cytoskeleton of eukaryotes are a major contributor to the mechanical properties of cells. The hierarchical build-up of the filaments from subunits and the formation of networks will be studied. We will combine nano- and micro-imaging and scattering methods with microfluidic techniques. In particular, our aim is to understand the influence of mono- or multivalent ions on the assembly and the resulting mechanical properties.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 755: Nanoscale Photonic Imaging
• Applicant Institution: Georg-August-Universität Göttingen
• Project Head: Professorin Dr. Sarah Köster