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Regulation of the T cell response during malaria (B04)

Subject Area Immunology
Term from 2010 to 2021
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 80750187
 
Protection against malaria can be achieved by experimental induction of liver-stage infection when the subsequent blood-stage is prevented by using attenuated sporozoites or by antimalarial treatment. The blood-stage is accompanied by induction of Tr1-like cells. These cells will be further characterized by “next-generation sequencing” and high-content flow cytometry. Different subsets of Tr1-like cells will be tested for their regulatory capacity especially wit regard to their capability to prevent liver-stage immunity.
DFG Programme Collaborative Research Centres
Applicant Institution Universität Hamburg
 
 

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