Interfacial chemistry and 3-D analysis of interfaces of implants and osteoporotic bone ((05) M05)

• Subject Area: Physical Chemistry of Solids and Surfaces, Material Characterisation ; Biomaterials
• Term: from 2010 to 2019
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 107540325

Project M5 focuses on mass spectrometry imaging of bone, bone cells and the bone/biomaterial interface. The in funding period 2 initiated plasma functionalization of the inner surfaces of porous titanium alloys shall be completed. Alongside the investigation of the bone quality itself, drug detection and release from the biomaterial as well as dispersion within bone are important issues. Studies are carried out on samples from the T projects. In addition, model studies on bone cells concerning drug and biomaterial components uptake will be performed.

• DFG Programme: CRC/Transregios
• Subproject of: TRR 79: Materials for Tissue Regeneration within Systemically Altered Bone
• Applicant Institution: Justus-Liebig-Universität Gießen
• Project Heads: Professor Dr. Jürgen Janek; Professor Dr. Marcus Rohnke