Verlängerungsantrag Heisenberg-Professur

• Applicant: Professor Dr. Stephan Weidinger
• Subject Area: Dermatology
• Term: from 2010 to 2015
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 173936455

• Final Report Year: 2015

Final Report Abstract

No abstract available

Publications

• Meta-analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease. Journal of Allergy and Clinical Immunology, Vol. 123. 2009, Issue 6, pp. 1361–1370.
  Rodriguez E., Baurecht H., Herberich E., Wagenpfeil S., Brown S.J., Cordell H.J., Irvine A.D., Weidinger S.
  (See online at https://doi.org/10.1016/j.jaci.2009.03.036)
• Stratum corneum lipids, skin barrier function and filaggrin mutations in patients with atopic eczema. Allergy, Vol. 65. 2010, Issue 7, pp. 911-918.
  Jungersted J.M., Scheer H., Mempel M., Baurecht H., Cifuentes L., Høgh J.K., Hellgren L.I., Jemec G.B., Agner T., Weidinger S.
  (See online at https://doi.org/10.1111/j.1398-9995.2010.02326.x)
• Mutual antagonism of T cells causing psoriasis and atopic eczema. New England Journal of Medicine, Vol. 365. 2011, pp. 231-238.
  Eyerich S., Onken A.T., Weidinger S., Franke A., Nasorri F., Pennino D., Grosber M., Pfab F., Schmidt-Weber C.B., Mempel M., Hein R., Ring J., Cavani A., Eyerich K.
  (See online at https://dx.doi.org/10.1056/NEJMoa1104200)
• Network-based SNP meta-analysis identifies joint and disjoint genetic features across common human diseases. BMC Genomics, Vol. 13. 2012: 490.
  Arnold M., Hartsperger M.L., Baurecht H., Rodríguez E., Wachinger B., Franke A, Kabesch M., Win-kelmann J., Pfeufer A., Romanos M., Illig T., Mewes H.W., Stümpflen V., Weidinger S.
  (See online at https://doi.org/10.1186/1471-2164-13-490)
• A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis. Human Molecular Genetics, Vol. 22. 2013, Issue 23, pp. 4841–4856.
  Weidinger S., Willis-Owen S.A., Kamatani Y., Baurecht H., Morar N., et al.
  (See online at https://doi.org/10.1093/hmg/ddt317)
• High-density genotyping study identifies four new susceptibility loci for atopic dermatitis. Nature Genetics, Vol. 45. 2013, pp. 808–812.
  Ellinghaus D., Baurecht H., Esparza-Gordillo J., Rodríguez E., Weidinger S., et al.
  (See online at https://doi.org/10.1038/ng.2642)
• A common atopy-associated variant in the Th2 cytokine locus control region impacts transcriptional regulation and alters SMAD3 and SP1 binding. Allergy, Vol. 69. 2014, Issue 5, pp. 632-642.
  Kretschmer A., Möller G., Lee H, Laumen H., Toerne C., Schramm K., Weidinger S., et al.
  (See online at https://doi.org/10.1111/all.12394)
• An integrated epigenetic and transcriptomic analysis reveals distinct tissue-specific patterns of DNA methyl-ation associated with atopic dermatitis. Journal of Investigative Dermatology, Vol. 134. 2014, Issue 7, pp. 1873-1883.
  Rodríguez E., Baurecht H., Wahn A.F., Kretschmer A., Hotze M., Zeilinger S., Weidinger S., et al.
  (See online at https://doi.org/10.1038/jid.2014.87)