Characterisation of epigenetic mechanisms in transcriptional regulation in hypoxia

• Applicant: Dr. Lina Sciesielski
• Subject Area: Anatomy and Physiology
• Term: from 2010 to 2012
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 179875606

• Final Report Year: 2012

Final Report Abstract

No abstract available

Publications

• Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression. Nature Genetics, Vol. 44. 2012, pp. 420–425.
  Schödel J., Bardella C., Sciesielski L.K., Brown J.M., Pugh C.W., Buckle V., Tomlinson I.P., Ratcliffe P.J., Mole D.R.
  (See online at https://doi.org/10.1038/ng.2204)
• Heterogeneous effects of direct hypoxia pathway activation in kidney cancer. PLoS One, Vol. 10. 2015, Issue 8: e0134645.
  Salama R., Masson N., Simpson P., Sciesielski L.K., Sun M., Tian Y.M., Ratcliffe PJ., Mole D.R.
  (See online at https://doi.org/10.1371/journal.pone.0134645)