Circuit mechanisms underlying signal processing in the mammalian retina during saccades (C01)

• Subject Area: Cognitive, Systems and Behavioural Neurobiology
• Term: from 2011 to 2022
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 154113120

This project aims at elucidating how the retina processes visual signals in the context of saccadic eye movements. We will use multielectrode arrays and patch-clamp recordings to measure neural signals from isolated mouse retinas while projecting saccade-like shifts of visual stimuli onto the photoreceptors. Using variations in stimulus parameters and pharmacological intervention, we will investigate the mechanisms that shape saccade-triggered responses, in particular the role of inhibitory interactions. Furthermore, we will aim at devising mathematical models that capture responses under saccade-like shifts of natural images and at generalizing the studies to fixational eye movements and eye blinks.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 889: Cellular Mechanisms of Sensory Processing
• Applicant Institution: Georg-August-Universität Göttingen
• Project Head: Professor Dr. Tim Gollisch