4D-Multiphoton intravital microscopy in mouse models of immune cell trafficking (Z01)

• Subject Area: Immunology
• Term: from 2011 to 2023
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 165054336

Multiphoton intravital microscopy (MP-IVM) allows the study of immune cell trafficking in small animal models at high penetration depth and with great spatial and temporal resolution. We have established a broad variety of mouse models for inflammatory diseases and bacterial infections (biosafety level S2). Further supported by recent software developments and state-of-the-art devices for tissue immobilization, the MP-IVM platform enables researchers to gain deep insight into immune cell functions in development and disease.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 914: Trafficking of Immune Cells in Inflammation, Development and Disease
• Applicant Institution: Ludwig-Maximilians-Universität München
• Project Heads: Dr. Hellen Ishikawa-Ankerhold; Dr. Alexander Khandoga, until 6/2019; Professor Dr. Steffen Massberg