Functional role of skin resident effector memory T cells in host protection against infections and behaviour in healthy skin and cutaneous lymphomas.

• Applicant: Professorin Dr. Emmanuella Guenova
• Subject Area: Dermatology
• Term: from 2012 to 2014
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 209176247

• Final Report Year: 2015

No abstract available

Publications

• Low dose high-dose-rate brachytherapy in the treatment of facial lesions in cutaneous T-cell lymphoma. J Am Acad Dermatol 2013 69(1):61-5
  DeSimone JA, Guenova E, Carter JB, Chaney KS, Aldridge JR, Noell CM, Dorosario AA, Hansen JL, Kupper TS, Devlin PM
  
• Th2 cytokines from malignant cells suppress Th1 responses and enforce a global Th2 bias in leukemic cutaneous T-cell lymphoma. Clin Cancer Res. 2013 19(14):3755-63
  Guenova, Emmanuella; Watanabe, Rei; Teague, Jessica E.; Desimone, Jennifer A.; Jiang, Ying; Dowlatshahi, Mitra; Schlapbach, Christoph; Schaekel, Knut; Rook, Alain H.; Tawa, Marianne; Fisher, David C.; Kupper, Thomas S. & Clark, Rachael A.
  
• Cutaneous Innate Immune Sensing of Toll-like Receptor 2-6 Ligands Suppresses T Cell Immunity by Inducing Myeloid-Derived Suppressor Cells. Immunity. 2014 41(5):762-75
  Skabytska, Yuliya; Wölbing, Florian; Günther, Claudia; Köberle, Martin; Kaesler, Susanne; Chen, Ko-Ming; Guenova, Emmanuella; Demircioglu, Doruk; Kempf, Wolfgang E.; Volz, Thomas; Rammensee, Hans-Georg; Schaller, Martin; Röcken, Martin; Götz, Friedrich & Biedermann, Tilo
  
• Human Th9 cells are skin-tropic and have autocrine and paracrine pro-inflammatory capacity. Sci Transl Med 2014 6(219):219ra8
  Schlapbach, Christoph; Gehad, Ahmed; Yang, Chao; Watanabe, Rei; Guenova, Emmanuella; Teague, Jessica E.; Campbell, Laura; Yawalkar, Nikhil; Kupper, Thomas S. & Clark, Rachael A.
  
• Systemic corticosteroids for subcutaneous panniculitis-like T-cell lymphoma. Br J Dermatol 2014 171(4):891-4
  Guenova, E.; Schanz, S.; Hoetzenecker, W.; DeSimone, J.A.; Mehra, T.; Voykov, B.; Urosevic‐Maiwald, M.; Berneburg, M.; Dummer, R.; French, L.E.; Kerl, K.; Kamarashev, J.; Fierlbeck, G. & Cozzio, A.
  
• IL-4 abrogates TH17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenting cells. Proc Natl Acad Sci USA. 2015 112(7):2163-8
  Guenova, Emmanuella; Skabytska, Yuliya; Hoetzenecker, Wolfram; Weindl, Günther; Sauer, Karin; Tham, Manuela; Kim, Kyu-Won; Park, Ji-Hyeon; Seo, Ji Hae; Ignatova, Desislava; Cozzio, Antonio; Levesque, Mitchell P.; Volz, Thomas; Köberle, Martin; Kaesler, Susanne; Thomas, Peter; Mailhammer, Reinhard; Ghoreschi, Kamran; Schäkel, Knut; ... & Biedermann, Tilo