Die Rolle der Basalganglien für die Modulation von Reaktionsauswahlprozessen auf einem "Seriell- Parallel-Kontinuum"

• Applicant: Professor Dr. Christian Beste
• Subject Area: General, Cognitive and Mathematical Psychology
• Term: from 2012 to 2019
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 209182214

• Final Report Year: 2020

Final Report Abstract

To summarize, the projected yielded to be achieved insights into the neurobiology and neurophysiology underlying responses selection processes during multitasking with special emphasis on the response selection strategies/modes (i.e. serial or parallel). The findings provided the basis for further research and the establishment of the chair of “Cognitive Neurophysiology” at TU Dresden. The cognitive processes being investigated as part of the Emmy Noether funding are still investigated as a central part of the scientific mission of the Chair “Cognitive Neurophysiology”. As such, the Emmy Noether project led to a sustained scientific program.

Publications

• (2012). Mechanisms mediating parallel action monitoring in fronto-striatal circuits. NeuroImage, 62(1), 137–146
  Beste, C., Ness, V., Lukas, C., Hoffmann, R., Stüwe, S., Falkenstein, M., & Saft, C.
  (See online at https://doi.org/10.1016/j.neuroimage.2012.05.019)
• (2013). Learning without training. Current Biology: CB, 23(11), R489-499
  Beste, C., & Dinse, H. R.
  (See online at https://doi.org/10.1016/j.cub.2013.04.044)
• (2014). DRD1 and DRD2 genotypes modulate processing modes of goal activation processes during action cascading. The Journal of Neuroscience: The Official Journal of the Society for Neuroscience, 34(15), 5335–5341
  Stock, A.-K., Arning, L., Epplen, J. T., & Beste, C.
  (See online at https://doi.org/10.1523/JNEUROSCI.5140-13.2014)
• (2014). Feeling safe in the plane: neural mechanisms underlying superior action control in airplane pilot trainees--a combined EEG/MRS study. Human Brain Mapping, 35(10), 5040–5051
  Yildiz, A., Quetscher, C., Dharmadhikari, S., Chmielewski, W., Glaubitz, B., Schmidt-Wilcke, T., Edden, R., Dydak, U., & Beste, C.
  (See online at https://doi.org/10.1002/hbm.22530)
• (2014). Latent Toxoplasma gondii infection leads to improved action control. Brain, Behavior, and Immunity, 37, 103–108
  Stock, A.-K., Heintschel von Heinegg, E., Köhling, H.-L., & Beste, C.
  (See online at https://doi.org/10.1016/j.bbi.2013.11.004)
• (2014). Psychophysiological mechanisms of interindividual differences in goal activation modes during action cascading. Cerebral Cortex (New York, N.Y.: 1991), 24(8), 2120–2129
  Mückschel, M., Stock, A.-K., & Beste, C.
  (See online at https://doi.org/10.1093/cercor/bht066)
• (2015). A causal role of the right inferior frontal cortex in implementing strategies for multi-component behaviour. Nature Communications, 6, 6587
  Dippel, G., & Beste, C.
  (See online at https://doi.org/10.1038/ncomms7587)
• (2015). Complex sensorimotor transformation processes required for response selection are facilitated by the striatum. NeuroImage, 123, 33–41
  Stock, A.-K., Ness, V., & Beste, C.
  (See online at https://doi.org/10.1016/j.neuroimage.2015.08.036)
• (2015). Parallel and serial processing in dual-tasking differentially involves mechanisms in the striatum and the lateral prefrontal cortex. Brain Structure & Function, 220(6), 3131–3142
  Yildiz, A., & Beste, C.
  (See online at https://doi.org/10.1007/s00429-014-0847-0)
• (2017). The norepinephrine system and its relevance for multi-component behavior. NeuroImage, 146, 1062–1070
  Mückschel, M., Gohil, K., Ziemssen, T., & Beste, C.
  (See online at https://doi.org/10.1016/j.neuroimage.2016.10.007)