The role of parasitic phosphatidylserine in the infection of human polymophonuclear neutrophil granulocytes (PMN) by Leishmania major

Applicant Professor Dr. Ger van Zandbergen

Subject Area Parasitology and Biology of Tropical Infectious Disease Pathogens

Term from 2005 to 2010

Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 21110843

Final Report Year 2010

Final Report Abstract

No abstract available

2006. Leishmania disease development depends on the presence of apoptotic promastigotes in the virulent inoculum. Proc. Natl. Acad. Sci. U. S. A. 103:13837-13842
van Zandbergen, G., A. Bollinger, A. Wenzel, S. Kamhawi, R. Voll, M. Klinger, A. Muller, C. Holscher, M. Herrmann, D. Sacks, W. Solbach, and T. Laskay
2009. Are neutrophils important host cells for Leishmania parasites? Trends Parasitol. 25:505-510
Ritter, U., F. Frischknecht, and G. van Zandbergen
2009. Chlamydia pneumoniae hides inside apoptotic neutrophils to silently infect and propagate in macrophages. PLoS. One. 4:e6020
Rupp, J., L. Pfleiderer, C. Jugert, S. Moeller, M. Klinger, K. Dalhoff, W. Solbach, S. Stenger, T. Laskay, and G. van Zandbergen
2009. Lipoxin A4 receptor dependent leishmania infection. Autoimmunity. 42:331-333
Wenzel, A. and G. van Zandbergen
2010. Phagocytosis of apoptotic cells by neutrophil granulocytes: diminished proinflammatory neutrophil functions in the presence of apoptotic cells. J. Immunol. 184:391-400
Esmann, L., C. Idel, A. Sarkar, L. Hellberg, M. Behnen, S. Moller, G. van Zandbergen, M. Klinger, J. Kohl, U. Bussmeyer, W. Solbach, and T. Laskay