Towards in-vivo monitoring and stimulation of early callus formation by quantitative focused ultrasound

• Applicant: Professor Dr. Kay Raum
• Subject Area: Orthopaedics, Traumatology, Reconstructive Surgery
• Term: from 2012 to 2015
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 213425253

• Final Report Year: 2015

Final Report Abstract

No abstract available

Publications

• Age affects the bone healing kinetics in a rat osteotomy model, 4th European Symposium on Ultrasonic Characterization of Bone, Jyväskylä, Finnland, 2011,
  Sauer,K., Rohrbach,D., Strube,P., Preininger,B., Raum, K.
  
• Non-invasive monitoring of callus formation by quantitative focused ultrasound (QUS), The Baltic Bone and Cartilage Conference: Malmö, Sweden, October 12-14, 2011: Program & Abstracts. 2011
  Preininger,B., Hesse,B., Rohrbach,D., Perka.C., Raum,K.
  
• Non-invasive monitoring of callus formation by quantitative focused ultrasound (QUS): Fundamentals by numerical sound propagation simulations in phantoms and rat femora, Osteologie 20 (Suppl. 1), 2011, 7
  Rohrbach,D., Hesse,B., Preininger,B., Raum,K., Perka,C.
  
• Noninvasive functional assessment of a rat femur model and phantoms using quantitative focused ultrasound (QUS): A pilot study. 4th European Symposium on Ultrasonic Characterization of Bone, Jyväskylä, Finnland, 2011
  Rohrbach,D., Hesse,B., Preininger,B., Raum K.
  
• Towards non-invasive monitoring of callus formation in small animals by quantitative focused ultrasound (QUS): Assessment of soft and mineralized tissue formation in a rat bone healing model, Osteologie 20 (Suppl. 1), 2011, 8
  Hesse,B., Rohrbach,D., Raum,K., Preininger,B., Perka,C.
  
• Assessment of soft and mineralized tissue formation in a rat bone healing model using quantitative ultrasound (QUS). The Journal of the Acoustical Society of America 04/2012; 131(4):3458
  Rohrbach,D., Hesse,B., Preininger,B., Perka,C., Raum K.
  
• Histogram feature-based classification improves differentiability of early bone healing stages from micro-computed tomographic data, J Comput. Assist. Tomogr. 36 (4), 2012, 469-476
  Preininger,B., Hesse,B., Rohrbach,D., Varga,P., Gerigk,H., Langer,M., Peyrin,F., Perka,C., Raum,K.
  
• Nicht-invasives Kallusmonitoring mittels quantitativem Ultraschall, Deutscher Kongress für Orthopädie und Unfallchirurgie
  Preininger,B., Rohrbach,D., Hesse,B., Gerigk,H., Perka,C., Raum,K.
  
• On the role of quantitative ultrasound (QUS) in fracture healing monitoring: what is next?, 5th European Symposium on Ultrasonic Characterization of Bone, Granada, Spain, 2013
  Machado,C.B., Rohrbach,D., Pereira,W.C.A., Laugier,P., Raum,K.
  
• The early phases of bone healing can be differentiated in a rat osteotomy model by focused transversetransmission ultrasound, Ultrasound Med. Biol. 39 (9), 2013, 1642-1653
  Rohrbach,D., Preininger,B., Hesse,B., Gerigk,H., Perka,C., Raum,K.
  
• Priors for X-ray in-line phase tomography of heterogeneous objects, Philos. Trans. A Math. Phys. Eng Sci. 372, 2014, 20130129
  Langer,M., Cloetens,P., Hesse,B., Suhonen,H., Pacureanu,A., Raum,K., Peyrin,F.
  
• Stimulation of bone repair with ultrasound: a review of the possible mechanic effects, Ultrasonics 54 (5), 2014, 1125-1145
  Padilla,F., Puts,R., Vico,L., Raum,K.
  
• (2016) Stimulation of Bone Repair with Ultrasound. In: Escoffre JM., Bouakaz A. (eds) Therapeutic Ultrasound. Advances in Experimental Medicine and Biology, vol 880. Springer, Cham. Chapter 21, pp 385-427. - 978-3-319-22535-7
  Padilla F., Puts R., Vico L., Guignandon A., Raum K.